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Safety Information

C7025

Sigma-Aldrich

Carbonic Anhydrase from bovine erythrocytes

BioReagent, suitable for GFC marker

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Synonym(s):
Carbonate Dehydratase, Carbonate Hydrolyase
CAS Number:
Enzyme Commission number:
EC Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.25

product line

BioReagent

Quality Level

form

powder

mol wt

~29,000

packaging

vial of 15 mg

suitability

suitable for GFC marker

storage temp.

−20°C

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Application

Carbonic Anhydrase from bovine erythrocytes is a bioreagent used in gel filtration chromatography, protein chromatography and plasma and blood proteins. Carbonic anhydrase has been used to study compounds widely known to have anticancer properties against human cancers and that act as diuretic, antibacterial, antifungal, antitubercular and leishmanicidal agents.
Gel filtration molecular weight marker

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

动植物源性产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Khushbu Rauniyar et al.
Scientific reports, 12(1), 18157-18157 (2022-10-29)
Vascular endothelial growth factor-C (VEGF-C) stimulates lymphatic vessel growth in transgenic models, via viral gene delivery, and as a recombinant protein. Expressing eukaryotic proteins like VEGF-C in bacterial cells has limitations, as these cells lack specific posttranslational modifications and provisions
Wisath Sae-Lee et al.
Cell reports, 40(3), 111103-111103 (2022-07-21)
Red blood cells (RBCs) (erythrocytes) are the simplest primary human cells, lacking nuclei and major organelles and instead employing about a thousand proteins to dynamically control cellular function and morphology in response to physiological cues. In this study, we define
Do Hyeon Kim et al.
Journal of microbiology and biotechnology, 30(12), 1905-1911 (2020-10-14)
Homoserine dehydrogenase (HSD) catalyzes the reversible conversion of L-aspartate-4- semialdehyde to L-homoserine in the aspartate pathway for the biosynthesis of lysine, methionine, threonine, and isoleucine. HSD has attracted great attention for medical and industrial purposes due to its recognized application
Fabrizio Carta et al.
Journal of medicinal chemistry, 56(11), 4691-4700 (2013-05-08)
Dithiocarbamates (DTCs) were recently discovered as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. A series of xanthates and a trithiocarbonate, structurally related to the DTCs, were prepared by reaction of alcohols/thiols with carbon disulfide in the presence of bases. These compounds
Leo Syrjänen et al.
Journal of medicinal chemistry, 56(18), 7372-7381 (2013-08-28)
Leishmaniasis is an infection provoked by protozoans belonging to the genus Leishmania. Among the many species and subsepecies of such protozoa, Leishmania donovani chagasi causes visceral leishmaniasis. A β-carbonic anhydrase (CA, EC 4.2.1.1) was cloned and characterized from this organism

Protocols

Gel filtration chromatography is an established method for determining the size and molecular mass of proteins.

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