C2791
N-(2-Chloro-4-pyridyl)-N′-phenylurea
applicable for cell culture, BioReagent
Synonym(s):
Forchlorfenuron, 4-CPPU, CPPU
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About This Item
Empirical Formula (Hill Notation):
C12H10ClN3O
CAS Number:
Molecular Weight:
247.68
NACRES:
NA.72
PubChem Substance ID:
UNSPSC Code:
10171502
MDL number:
Form:
powder
InChI
1S/C12H10ClN3O/c13-11-8-10(6-7-14-11)16-12(17)15-9-4-2-1-3-5-9/h1-8H,(H2,14,15,16,17)
SMILES string
Clc1cc(NC(=O)Nc2ccccc2)ccn1
InChI key
GPXLRLUVLMHHIK-UHFFFAOYSA-N
product line
BioReagent
form
powder
application(s)
agriculture
storage temp.
2-8°C
Quality Level
Application
N-(2-Chloro-4-pyridyl)-N′-phenylurea has been used as a supplement in Murashige and Tucker medium (MT) to culture thin cell layer (TCL) explants. It has also been used to spray on to the ovaries at anthesis for induction of parthenocarpic fruit.
Forchlorfenuron (CPPU) is a cytokinin that enhances in vitro direct shoot organogenesis of Citrus aurantium L. epicotyl segments.
Biochem/physiol Actions
N-(2-Chloro-4-pyridyl)-N′-phenylurea/ CPPU, a cytokinin-like plant growth regulator participates in chlorophyll biosynthesis, cell division and cell expansion. It helps to intensify fruit set and quickens fruit enlargement. CPPU modulates carbohydrate allocation.
CPPU is a cytokinin oxidase/dehydrogenase (CKO) inhibitor.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Carc. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
农药列管产品
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Effect of CPPU on carbohydrate and endogenous hormone levels in young macadamia fruit
Zeng H, et al.
PLoS ONE, 11(7), e0158705-e0158705 (2016)
Antonio Valverde et al.
Journal of agricultural and food chemistry, 58(5), 2818-2823 (2010-02-10)
This paper describes the application of liquid chromatography time-of-flight mass spectrometry (LC/TOF-MS), with electrospray ionization, for residue analysis of forchlorfenuron in tomato, zucchini and watermelon. The assessed method includes a sample preparation step based on the buffered QuEChERS approach. The
David Kopecný et al.
Biochimie, 92(8), 1052-1062 (2010-05-19)
Cytokinin oxidase/dehydrogenase (CKO) is a flavoenzyme, which irreversibly degrades the plant hormones cytokinins and thereby participates in their homeostasis. Several synthetic cytokinins including urea derivatives are known CKO inhibitors but structural data explaining enzyme-inhibitor interactions are lacking. Thus, an inhibitory
Masayuki Iwase et al.
Genes & genetic systems, 79(4), 199-206 (2004-10-30)
Septins, which are involved in cytokinesis, have been identified in a variety of fungi and animal cells. For analysis of the function of septin, drugs targeting septin would be useful; however, no such drugs have been available hitherto. By serendipity
Ji-Ye Hu et al.
Journal of AOAC International, 89(6), 1635-1640 (2007-01-18)
A method using solid-phase extraction for cleanup, followed by high-performance liquid chromatography with ultraviolet detection (HPLC/UV), was developed for the determination of forchlorfenuron residues in watermelon. The pesticide is extracted from the sample with acidic acetonitrile, and the extract is
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