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B7901

Sigma-Aldrich

Boric acid

suitable for electrophoresis, ≥99.5%

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About This Item

Linear Formula:
H3BO3
CAS Number:
10043-35-3
Molecular Weight:
61.83
EC Number:
233-139-2
MDL number:
MFCD00011337
UNSPSC Code:
12161700
eCl@ss:
38120104
PubChem Substance ID:
24892029
NACRES:
NA.25

vapor pressure

2.6 mmHg ( 20 °C)

Quality Level

200

Assay

≥99.5%

form

powder

technique(s)

electrophoresis: suitable

impurities

≤0.005% Insoluble in methanol

pH

8.2-10.1

mp

160 °C (dec.) (lit.)

solubility

H2O: 40 mg/mL, clear, colorless

density

1.43 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤0.001%
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.01%

cation traces

Ca: ≤0.005%
Fe: ≤0.001%
heavy metals (as Pb): ≤0.001%

suitability

suitable for electrophoresis (as a reagent)

storage temp.

room temp

SMILES string

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

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General description

Boric acid is a weak acid and is widely used in multi-purpose solutions (MPS) as a buffering agent. It is less toxic and non-volatile in nature.

Application

Boric acid has been used as a component of tris borate buffer:
  • for native polyacrylamide gel electrophoresis (PAGE) and denaturing urea-PAGE of tRNA samples(80)
  • for urea-polyacrylamide electrophoresis of RNA samples(81)
  • for agarose gel electrophoresis of DNA samples(82)

Biochem/physiol Actions

Boric acid is used in the periodontal therapy as an irrigation solution as it elicits bactericidal effects in microbial biofilms in root canal. Boric acid may favor osteoblastic activity and inhibit bone loss. It inhibits Candida albicans fungal infection and has potential to treat vaginal infection.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360FD

Hazard Classifications

Repr. 1B

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nonclinical safety evaluation of boric acid and a novel borate-buffered contact lens multi-purpose solution, Biotrue? multi-purpose solution
Lehmann DM, et al.
Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association, 33, S24-S32 (2010)
Antibacterial effect of different concentration of boric acid against enterococcus faecalis biofilms in root canal
Zan R, et al.
Marmara Dental Journal, 2, 76-80 (2013)
Antifungal mechanisms supporting boric acid therapy of Candida vaginitis
De Seta F, et al.
The Journal of Antimicrobial Chemotherapy, 63(2), 325-336 (2008)
Hye Ryeo Lee et al.
Journal of chromatography. A, 1346, 117-122 (2014-05-09)
In liquid phase microextraction, high enrichment factors can be obtained using an acceptor phase of small volume. By hanging an acceptor drop at the separation capillary tip, single drop microextraction (SDME) can be in-line coupled with capillary electrophoresis (CE). The
Albert Serrà et al.
ACS nano, 8(5), 4630-4639 (2014-05-03)
Electrodeposition from microemulsions using ionic liquids is revealed as a green method for synthesizing magnetic alloyed nanoparticles, avoiding the use of aggressive reducing agents. Microemulsions containing droplets of aqueous solution (electrolytic solution containing Pt(IV) and Co(II) ions) in an ionic
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