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Safety Information

B7901

Sigma-Aldrich

Boric acid

suitable for electrophoresis, ≥99.5%

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30 TABS
CN¥3,735.43

CN¥3,735.43

Available to ship onApril 14, 2025Details

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30 TABS
CN¥3,735.43

About This Item

Linear Formula:
H3BO3
CAS Number:
10043-35-3
Molecular Weight:
61.83
EC Number:
233-139-2
MDL number:
MFCD00011337
UNSPSC Code:
12161700
eCl@ss:
38120104
PubChem Substance ID:
24892029
NACRES:
NA.25

CN¥3,735.43

Available to ship onApril 14, 2025Details

Request a Bulk Order

grade

electrophoresis grade

vapor pressure

2.6 mmHg ( 20 °C)

Assay

≥99.5%

form

powder

technique(s)

electrophoresis: suitable

impurities

≤0.005% Insoluble in methanol

pH

8.2-10.1

mp

160 °C (dec.) (lit.)

solubility

H2O: 40 mg/mL, clear, colorless

density

1.43 g/cm3 at 20 °C

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11836153001

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manufacturer/tradename

Roche

manufacturer/tradename

Roche

manufacturer/tradename

Roche

manufacturer/tradename

Roche

packaging

pkg of 30 tablets (individually packed in foil blister packs)

packaging

pkg of 2 × 10 tablets (05892953001), pkg of 6 × 10 tablets (06538282001)

packaging

pkg of 30 tablets (individually packed in foil blister packs)

packaging

vial of 25 tablets

solubility

water: soluble

solubility

aqueous buffer: soluble

solubility

water: soluble

solubility

water: soluble

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

absorption

0.4 at 280 nm (1x solution)

absorption

0.4 at 280 nm (1x solution)

absorption

0.4 at 280 nm (1x solution)

absorption

-

General description

Boric acid is a weak acid and is widely used in multi-purpose solutions (MPS) as a buffering agent.[1] It is less toxic and non-volatile in nature.[2]

Application

Boric acid has been used as a component of tris borate buffer:
  • for native polyacrylamide gel electrophoresis (PAGE) and denaturing urea-PAGE of tRNA samples(80)
  • for urea-polyacrylamide electrophoresis of RNA samples(81)
  • for agarose gel electrophoresis of DNA samples(82)

Biochem/physiol Actions

Boric acid is used in the periodontal therapy as an irrigation solution as it elicits bactericidal effects in microbial biofilms in root canal. Boric acid may favor osteoblastic activity and inhibit bone loss.[2] It inhibits Candida albicans fungal infection and has potential to treat vaginal infection.[3]

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360FD

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCM9816
    BCCL8241
    BCCM1470
    BCCK4313
    BCCH9240

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    Find documentation for the products that you have recently purchased in the Document Library.

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    Antibacterial effect of different concentration of boric acid against enterococcus faecalis biofilms in root canal
    Zan R, et al.
    Marmara Dental Journal, 2, 76-80 (2013)
    Nonclinical safety evaluation of boric acid and a novel borate-buffered contact lens multi-purpose solution, Biotrue? multi-purpose solution
    Lehmann DM, et al.
    Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association, 33, S24-S32 (2010)
    Antifungal mechanisms supporting boric acid therapy of Candida vaginitis
    De Seta F, et al.
    The Journal of Antimicrobial Chemotherapy, 63(2), 325-336 (2008)
    Akie Shimotohno et al.
    Plant & cell physiology, 56(4), 620-630 (2015-02-12)
    Boron, an essential micronutrient, is transported in roots of Arabidopsis thaliana mainly by two different types of transporters, BORs and NIPs (nodulin26-like intrinsic proteins). Both are plasma membrane localized, but have distinct transport properties and patterns of cell type-specific accumulation
    Jing Li et al.
    American journal of physiology. Cell physiology, 306(10), C943-C960 (2014-03-22)
    The human solute carrier (SLC26) family of anion transporters consists of 10 members (SLCA1-11, SLCA10 being a pseudogene) that encode membrane proteins containing ~12 transmembrane (TM) segments with putative N-glycosylation sites (-NXS/T-) in extracellular loops and a COOH-terminal cytosolic STAS
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