B1682
BAD from mouse
≥70% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution
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recombinant
expressed in E. coli
Quality Level
description
full-length murine Bad with an N-terminal histidine-tag.
Assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
31 kDa
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Bad(12015)
Biochem/physiol Actions
Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.
Physical form
Supplied as a solution in phosphate buffered saline containing 250 mM imidizole and 50% glycerol.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
Certificates of Analysis (COA)
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