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Merck
CN

BAD

BCL2-associated agonist of cell death

别名:
BBC2, BCL2L8
物种:
UniProtKB ID:
基因ID:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

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Small Molecule - Antagonist

货号
说明
物种
2,3-二羟基萘, ≥98.0% (HPLC),
物种
human
4-联苯乙酸, 98%,
物种
human
联苯-4-羧酸, 95%,
物种
human
(±)-棉酚 来源于棉花种子, ≥95% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
物种反应性
human
应用
western blot
Anti-BAD (Ab-136) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
物种反应性
bovine, canine, human, mouse, rat
应用
immunoprecipitation (IP)
inhibition assay

western blot
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

Proteins

货号
说明
物种
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human BAD,
物种
human