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B1155

Sigma-Aldrich

bisBenzimide H 33258

powder, BioReagent, suitable for cell culture, ≥98% (HPLC and TLC)

Synonym(s):

2′-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi(1H-benzimidazole) trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazole trihydrochloride, BBIH, BXI-72, HOE 33258, Hoechst 33258, NSC334072

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100 ML
CN¥598.03

CN¥598.03

Available to ship onApril 23, 2025Details

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100 ML
CN¥598.03

About This Item

Empirical Formula (Hill Notation):
C25H24N6O · 3HCl
CAS Number:
23491-45-4
Molecular Weight:
533.88
Beilstein:
4088183
EC Number:
245-690-6
MDL number:
MFCD00012679
UNSPSC Code:
41106305
PubChem Substance ID:
24891565
NACRES:
NA.77

CN¥598.03

Available to ship onApril 23, 2025Details

Request a Bulk Order

product line

BioReagent

Quality Level

200

Assay

≥98% (HPLC and TLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 10 mg/mL
water and ethanol: 10 mg/mL

suitability

passes application test for fluorescence

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(=NCc3c2)c4ccc5NC(=NCc5c4)c6ccc(O)cc6

InChI

1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18;;;;/h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31);3*1H;1H2

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Show Differences

1 of 4

This Item
F7799SAB4503488SAB4300551
抗胆囊收缩素(26-33) (CCK-8) 兔抗 whole antiserum

C2581

抗胆囊收缩素(26-33) (CCK-8) 兔抗

抗-c-Fos 兔抗 IgG fraction of antiserum, buffered aqueous solution

F7799

抗-c-Fos 兔抗

Anti-CCKAR antibody produced in rabbit affinity isolated antibody

SAB4503488

Anti-CCKAR antibody produced in rabbit

Anti-KRT18 (Ab-33) antibody produced in rabbit affinity isolated antibody

SAB4300551

Anti-KRT18 (Ab-33) antibody produced in rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

whole antiserum

antibody form

IgG fraction of antiserum

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... CCK(885)

Gene Information

human ... FOS(2353)

Gene Information

human ... CCKAR(886)

Gene Information

human ... KRT18(3875)

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice

Application

bisBenzimide H 33258 is useful for staining DNA, chromosomes and nuclei. bisBenzimide H 33258 may be used for fluorescence microscopy or flow cytometry.
Excitation max. = 346 nm
Emission max. = 460 nm
bisBenzimide H 33258 is useful for staining DNA, chromosomes, and nuclei. May be used for fluorescence microscopy or flow cytometry.

Biochem/physiol Actions

bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor.
bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor. bisBenzimide H 33258 is a membrane-permeable, fluorescent DNA stain with low cytotoxicity that intercalate in A-T regions of DNA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Jared J Luxton et al.
    Cell reports, 33(10), 108457-108457 (2020-11-27)
    Telomere length dynamics and DNA damage responses were assessed before, during, and after one-year or shorter duration missions aboard the International Space Station (ISS) in a comparatively large cohort of astronauts (n = 11). Although generally healthy individuals, astronauts tended to
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    Animal reproduction science, 117(1-2), 166-177 (2009-04-18)
    This study investigates the mitochondrial (mt) distribution in canine ovarian oocytes examined at recovery time, as related to the reproductive cycle stage, and in oviductal oocytes. Ovarian Germinal Vesicle (GV) stage oocytes were recovered from bitches in anestrous (A, n=2)
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