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Safety Information

A9335

Sigma-Aldrich

Astaxanthin

≥92%

Synonym(s):

(3S,3′S)-3,3′-Dihydroxy-β,β-carotene-4,4′-dione

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About This Item

Empirical Formula (Hill Notation):
C40H52O4
CAS Number:
472-61-7
Molecular Weight:
596.84
EC Number:
207-451-4
MDL number:
MFCD00672621
UNSPSC Code:
12352200
PubChem Substance ID:
24277721

Assay

≥92%

storage temp.

−20°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C([C@@H](O)CC2(C)C)=O)C(C)(C)C[C@H](O)C1=O

InChI

1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1

InChI key

MQZIGYBFDRPAKN-UWFIBFSHSA-N

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Biochem/physiol Actions

Astaxanthin is a potent carotenoid antioxidant found in marine algae, red yeast and many other plant and animal sources. Animal studies indicate that it reduces blood glucose and ameliorates several parameters of the diabetic metabolic syndrome. It improves blood flow and vascular tone in models of hypertension. In vitro studies indicate that it upregulates connexin 43 and thus, may be chemopreventive against cancer.

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
024K1051
097K1301
037K1235
094K1179
105K1117

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Dietary effects on carotenoid composition in the marine harpacticoid copepod Nitokra lacustris
Rhodes, A.C.E.
Journal of Plankton Research, 29 (2007)
Nicholas M Wade et al.
The Journal of experimental biology, 211(Pt 9), 1512-1519 (2008-04-22)
The transition from juvenile to adult in the Australian western rock lobster, Panulirus cygnus (George), is preceded by a mass migration from inshore nursery reefs to offshore breeding grounds. Associated with this migration is a moult which results in the
W A Schroeder et al.
The Journal of biological chemistry, 270(31), 18374-18379 (1995-08-04)
Carotenoids have recently received considerable interest because of their potential in delaying or preventing degenerative diseases such as arteriosclerosis, cancer, and aging. In this study we show that the active oxygen species singlet oxygen (1O2) and peroxyl radicals differently affect
L Sacconi et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(9), 3124-3129 (2006-02-21)
Second-harmonic generation (SHG) has proven essential for the highest-resolution optical recording of membrane potential (Vm) in intact specimens. Here, we demonstrate single-trial SHG recordings of neuronal somatic action potentials and quantitative recordings of their decay with averaging at multiple sites
Florence Folmer et al.
Biochemical pharmacology, 78(6), 592-606 (2009-05-19)
The deregulated activation of NF-kappaB is associated with cancer development and inflammatory diseases. With an aim to find new NF-kappaB inhibitors, we purified and characterized compounds from extracts of the Fijian sponge Rhabdastrella globostellata, the crinoid Comanthus parvicirrus, the soft
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