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Merck
CN

A254

AIDA

solid

Synonym(s):

1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic acid, 1-Aminoindan-1, 5-dicarboxylic acid, UPF 523

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About This Item

Empirical Formula (Hill Notation):
C11H11NO4
CAS Number:
168560-79-0
Molecular Weight:
221.21
MDL number:
MFCD00672638
UNSPSC Code:
12352200
PubChem Substance ID:
24277957
NACRES:
NA.32

Key Documents

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form

solid

Quality Level

100

color

white

solubility

DMSO: 2 mg/mL

SMILES string

NC1(CCc2cc(ccc12)C(O)=O)C(O)=O

InChI

1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)

InChI key

LSTPKMWNRWCNLS-UHFFFAOYSA-N

Gene Information

human ... GRM1(2911)
rat ... Grm1(24414)

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Biochem/physiol Actions

Selective mGluR1 metabotropic glutamate receptor antagonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
110K4605
035K4711
040K4603

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An H Do et al.
Journal of neuroengineering and rehabilitation, 8, 49-49 (2011-08-27)
Many neurological conditions, such as stroke, spinal cord injury, and traumatic brain injury, can cause chronic gait function impairment due to foot-drop. Current physiotherapy techniques provide only a limited degree of motor function recovery in these individuals, and therefore novel
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PloS one, 7(8), e43417-e43417 (2012-09-01)
In the cerebellar glomerulus, GABAergic synapses formed by Golgi cells regulate excitatory transmission from mossy fibers to granule cells through feed-forward and feedback mechanisms. In acute cerebellar slices, we found that stimulating Golgi cell axons with a train of 10
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