A024
MECA
solid
Synonym(s):
5′-N-Methylcarboxamidoadenosine
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About This Item
Empirical Formula (Hill Notation):
C11H14N6O4
CAS Number:
Molecular Weight:
294.27
MDL number:
UNSPSC Code:
12352200
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form
solid
color
white
solubility
0.1 M HCl: soluble
H2O: slightly soluble
ethanol: slightly soluble
SMILES string
CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23
Gene Information
human ... ADORA2A(135) , ADORA2B(136)
Biochem/physiol Actions
A2 adenosine receptor agonist.
Regulatory Information
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R F Bruns et al.
Molecular pharmacology, 29(4), 331-346 (1986-04-01)
[3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuronamide) is known to bind to both the A1 and A2 subtypes of adenosine receptor in rat striatal membranes. In order to study the putative A2 component of [3H]NECA binding, we examined several compounds for the ability to selectively
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