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M79603

1-Methyl-2-pyrrolidinone

Name: 1-Methyl-2-pyrrolidinone
Brand: SIGALD

ReagentPlus^®, 99%

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Synonym(s):

1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

Empirical Formula (Hill Notation):

C₅H₉NO

CAS Number:

872-50-4

Molecular Weight:

99.13

Beilstein:

106420

EC Number:

212-828-1

MDL number:

MFCD00003193

UNSPSC Code:

12352005

PubChem Substance ID:

329818046

NACRES:

NA.21

vapor density

3.4 (vs air)

Quality Level

100

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

product line

ReagentPlus^®

Assay

99%

form

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

impurities

≤0.1% water (Karl Fischer)

color

APHA: ≤50

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

density

1.028 g/mL at 25 °C (lit.)

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

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Related Categories

Solvents

Application

Undergoes condensation reactions with arylthioacetamides and methyl salicylates. Versatile solvent for water miscible applications.

Other Notes

A Greener alternative is available for many NMP applications, Cyrene (807796)

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

greener alternative product

Product No.

Description

Pricing

Signal Word

Danger

Hazard Statements

H315,H319,H335,H360D

Precautionary Statements

P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

Pensky-Martens closed cup

Flash Point(C)

Pensky-Martens closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Journal of Organic Chemistry, 58, 7277-7277 (1993)

Large-scale production of liposomes containing monomeric zinc phthalocyanine by controlled dilution of organic solvents.

U Isele et al.

Journal of pharmaceutical sciences, 83(11), 1608-1616 (1994-11-01)

This work describes the development of an organic solvent dilution method suitable for the large scale manufacturing of small unilamellar liposomes containing the water-insoluble photosensitizer zinc phthalocyanine in the monomeric state. N-Methyl pyrrolidone (NMP)/tert-butyl alcohol was selected as water miscible

J. Mol. Catal., 85, L109-L109 (1993)

Journal of the Chemical Society. Chemical Communications, 1437-1437 (1994)

Influence of heat curing on structure and physicochemical properties of phenolic acid loaded proteinaceous electrospun fibers.

Yun Ping Neo et al.

Journal of agricultural and food chemistry, 62(22), 5163-5172 (2014-05-16)

Effects of heat treatment on structure and physicochemical properties of zein (Ze) and gallic acid loaded zein (Ze-GA) electrospun fiber mats were investigated. The electrospun fiber mats displayed different surface and physicochemical properties after being heat-cured at 150 °C for

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