Skip to Content
Merck
CN

209198

Copper(II) sulfate pentahydrate

ACS reagent, ≥98.0%

Synonym(s):

Cupric sulfate pentahydrate, Sulfuric acid, copper(II) salt (1:1) pentahydrate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CuSO4 · 5H2O
CAS Number:
7758-99-8
Molecular Weight:
249.69
NACRES:
NA.21
PubChem Substance ID:
329752057
UNSPSC Code:
12352302
EC Number:
231-847-6
MDL number:
MFCD00149681
Assay:
≥98.0%
98.0-102.0% (ACS specification)
Grade:
ACS reagent
Form:
crystals

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Copper(II) sulfate pentahydrate, ACS reagent, ≥98.0%

InChI key

JZCCFEFSEZPSOG-UHFFFAOYSA-L

InChI

1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2

SMILES string

O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O

grade

ACS reagent

vapor pressure

7.3 mmHg ( 25 °C)

assay

≥98.0%
98.0-102.0% (ACS specification)

form

crystals

reaction suitability

reaction type: click chemistry
reagent type: catalyst
core: copper

pH

3.5-4.5 (20 °C, 50 g/L)

mp

110 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.001%

cation traces

Ca: ≤0.005%
Fe: ≤0.003%
K: ≤0.01%
Na: ≤0.02%
Ni: ≤0.005%

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Copper(II) sulfate pentahydrate can be used as a catalyst:      
  • In acetylation of alcohols and phenols in the presence of acetic anhydride.      
  • To synthesize various ynamides via intramolecular coupling of amides with alkynyl bromides.

It can also be used as a template in the synthesis of copper(II) ion-imprinted polymers using vinylpyridine and methacrylic acid as functional monomers. This polymer is used to quantify Cu2+ ion by using flame atomic absorption spectroscopy.

Features and Benefits

CuSO4.5H2O is an inexpensive, safe catalyst to be used in various organic transformations. It can also be recovered and reused in another reaction.

General description

Copper(II) sulfate pentahydrate is a Lewis acid catalyst commonly used to promote acid-catalyzed organic transformations. It can also act as an effective redox catalyst in combination with other mixed oxidizing agents.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN9057
MKCZ6669
MKCZ6668
BCCN5506
BCCN3596

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Copper (II) Sulfate.
Hoffman RV, et al.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
Copper (II) sulfate pentahydrate (CuSO4. 5H2O): a green catalyst for solventless acetylation of alcohols and phenols with acetic anhydride.
Heravi MM, et al.
Journal of the Brazilian Chemical Society, 17(5), 1045-1047 (2006)
Wei Zhao et al.
Dalton transactions (Cambridge, England : 2003), (8)(8), 1509-1517 (2005-04-13)
Three novel metal-organic frameworks (MOFs), [Cu(1)SO4].H2O (4), [Cu2(2)2(SO4)2].4H2O (5) and [Cu(3)(H2O)]SO4.5.5H2O (6), were obtained by hydrothermal reactions of CuSO4.5H2O with the corresponding ligands, which have different flexibility. The structures of the synthesized complexes were determined by single-crystal X-ray diffraction analyses.
Xuan Ming et al.
Cell research, 30(11), 980-996 (2020-06-26)
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity. Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question. A replication-coupled DNA methylation maintenance model was
Damijana Urankar et al.
Journal of combinatorial chemistry, 10(6), 981-985 (2008-10-17)
Azoamides, previously established as bioactive intracellular GSH-depleting agents, were decorated with a terminal alkyne moiety to 4 and then were transformed, by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), into different ligand-arm functionalized azoamides 6. Azides 5 having ligand-arms amenable for binding to
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service