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Y0000197

Ondansetron for LC system suitability

Name: Ondansetron for LC system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):

Ondansetron hydrochloride dihydrate, 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride, GR 38032F

Empirical Formula (Hill Notation):

C₁₈H₁₉N₃O · HCl · 2H₂O

CAS Number:

103639-04-9

Molecular Weight:

365.85

MDL number:

MFCD00374371

UNSPSC Code:

41116107

PubChem Substance ID:

329830879

NACRES:

NA.24

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Y0000196

Ondansetron for TLC system suitability

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Ondansetron hydrochloride dihydrate

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1478571

Ondansetron

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Cetirizine for peak identification

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1478593

Ondansetron Related Compound A

Y0001345

Ondansetron impurity A

USP

1478630

Ondansetron Resolution Mixture

M1625000

Methylnitrosoindoline

grade

pharmaceutical primary standard

API family

ondansetron

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H]O[H].[H]O[H].Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C

InChI

1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

InChI key

VRSLTNZJOUZKLX-UHFFFAOYSA-N

Gene Information

human ... HTR3A(3359)

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Related Categories

Analytical Reference Standards

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ondansetron for LC system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

5-HT₃serotonin receptor antagonist

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

PHR1141

Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1478618

1478593

1478629

PHR2224

PHR2223

PHR2221

Pictograms

GHS06,GHS05,GHS09

Signal Word

Danger

Hazard Statements

H301,H318,H410

Precautionary Statements

P264 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P391

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Clinical and economic impact of oral ondansetron for vomiting in a pediatric emergency department.

Daniel Hervás et al.

Pediatric emergency care, 28(11), 1166-1168 (2012-11-02)

In this study, we determine the clinical impact of 1 dose of oral ondansetron for children with vomiting and evaluate the economic consequences of its use. The strategies compared were administering oral ondansetron in addition to oral rehydration therapy (group

Prophylactic ondansetron does not prevent shivering or decrease shivering severity during cesarean delivery under combined spinal epidural anesthesia: a randomized trial.

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Cesarean delivery is commonly performed under regional anesthesia, which is often associated with maternal shivering. This can cause distress and interfere with monitoring. The study objective was to evaluate the antishivering efficacy of ondansetron, which reduces the incidence and severity

Development of HPTLC method for the estimation of ondansetron hydrochloride in bulk drug and sublingual tablets.

Ali Mujtaba et al.

Drug testing and analysis, 5(2), 122-125 (2013-02-16)

A new, simple, rapid, accurate and precise high performance thin layer chromatography (HPTLC) method has been developed for the estimation of ondansetron hydrochloride in bulk and sublingual tablets. The mobile phase composition was chloroform : ethyl acetate : methanol :

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