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T0781

Supelco

3,5,5,-Trimethyloxazolidine-2,4-dione

analytical standard

Synonym(s):

Trimethadione

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About This Item

Empirical Formula (Hill Notation):
C6H9NO3
CAS Number:
127-48-0
Molecular Weight:
143.14
EC Number:
204-845-8
MDL number:
MFCD00047084
UNSPSC Code:
41116107
PubChem Substance ID:
329826621
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CN1C(=O)OC(C)(C)C1=O

InChI

1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3

InChI key

IRYJRGCIQBGHIV-UHFFFAOYSA-N

Gene Information

human ... CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H312 + H332,H360

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Haiyan Shen et al.
Hearing research, 226(1-2), 52-60 (2007-02-13)
Cochlear noise injury is the second most frequent cause of sensorineural hearing loss, after aging. Because calcium dysregulation is a widely recognized contributor to noise injury, we examined the potential of calcium channel blockers to reduce noise-induced hearing loss (NIHL)
H Nakamura et al.
Journal of clinical pharmacy and therapeutics, 26(6), 417-424 (2001-11-28)
The trimethadione (TMO) tolerance test was performed to evaluate its usefulness in the assessment of hepatic functional reserve in patients with biliary atresia. Nineteen patients with biliary atresia after hepatic portoenterostomy (age range: 2 months to 25 years; sex: 6
E Tanaka et al.
Journal of clinical pharmacy and therapeutics, 28(6), 493-496 (2003-12-04)
Trimethadione (TMO), an antiepileptic drug, may be used as a candidate for estimating hepatic drug-oxidizing activity. While TMO metabolism is mainly catalysed by CYP2C9, CYP2E1 and CYP3A4 the contribution of the different isoforms is unclear. In this study, we determined
James J Collins et al.
Experimental gerontology, 41(10), 1032-1039 (2006-07-29)
The identification and analysis of compounds that delay aging and extend lifespan is an important aspect of gerontology research; these studies can test theories of aging, lead to the discovery of endogenous systems that influence aging, and establish the foundation
Matthew E Barton et al.
European journal of pharmacology, 521(1-3), 79-85 (2005-09-21)
The purpose of the present study was to explore the analgesic effects of the low voltage-activated T-type Ca2+ channel blockers ethosuximide, trimethadione, and mibefradil in persistent and acute nociceptive tests. The anticonvulsant effects of the compounds were also determined in
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