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RDD040

Sigma-Aldrich

Sodium dodecyl sulfate

BioReagent, suitable for electrophoresis, for molecular biology, ≥98.5% (GC), free-flowing, Redi-Dri™

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Synonym(s):
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
151-21-3
Molecular Weight:
288.38
Beilstein:
3599286
MDL number:
MFCD00036175
NACRES:
NA.25

grade

for molecular biology

Quality Level

100

description

anionic

product line

BioReagent
Redi-Dri™

Assay

≥98.5% (GC)

quality

free-flowing

mol wt

micellar 18,000

aggregation number

62

technique(s)

electrophoresis: suitable

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

anion traces

chloride (Cl-): ≤500 ppm
phosphate (PO43-): ≤10 ppm

cation traces

heavy metals (as Pb): ≤10 ppm

absorption

≤0.1 at 260 at 3%
≤0.1 at 280 at 3%

HLB

40

suitability

suitable for electrophoresis

foreign activity

DNase, RNase, none detected

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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General description

Sodium dodecyl sulfate (SDS) is an amphipathic detergent commonly used for denaturing proteins. SDS has a long-chain aliphatic group, with negatively charged sulfate groups that coat the surface of proteins, causing them to lose their quaternary structure.

Application

Sodium dodecyl sulfate has been used:
  • in chromatin immunoprecipitation
  • in SDS-polyacrylamide gel electrophoresis (SDS-PAGE)
  • as a component of radioimmunoprecipitation assay buffer for immunoblotting
Anionic detergent

Analysis Note

Tested for use in denatured polyacrylamide gel electrophoresis.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Regulatory Information

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