Skip to Content
Merck
CN
All Photos(1)

Documents

R0600000

Riboflavin

European Pharmacopoeia (EP) Reference Standard

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
(−)-Riboflavin, Lactoflavin, Vitamin B2, Vitamin G
Empirical Formula (Hill Notation):
C17H20N4O6
CAS Number:
83-88-5
Molecular Weight:
376.36
Beilstein:
97825
MDL number:
MFCD00005022
UNSPSC Code:
41116107
PubChem Substance ID:
329823988
NACRES:
NA.24

biological source

fermentation/recombinant (Bacillus subtilis)

grade

pharmaceutical primary standard

Agency

EP

API family

riboflavin

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

290 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

InChI key

AUNGANRZJHBGPY-SCRDCRAPSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Riboflavin is a type of vitamin B that plays a vital role in human nutrition and growth. It finds potential applications in biochemical redox reactions and is present in several foodstuffs, energy drinks, and vitamin formulations.

Application

Riboflavin may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

PHR1054

Riboflavin, Pharmaceutical Secondary Standard; Certified Reference Material

1603006

Riboflavin, United States Pharmacopeia (USP) Reference Standard

R0630000

Riboflavin sodium phosphate, European Pharmacopoeia (EP) Reference Standard

PHR1297

Phosphated Riboflavin (Riboflavin Sodium Phosphate), Pharmaceutical Secondary Standard; Certified Reference Material

Y0000757

Riboflavin for peak identification, European Pharmacopoeia (EP) Reference Standard

1535700

Phosphated Riboflavin, United States Pharmacopeia (USP) Reference Standard

PHR1936

Riboflavin Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

BP459

Riboflavin sodium phosphate, British Pharmacopoeia (BP) Reference Standard

PHR2570

Riboflavin Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Simultaneous determination of nicotinamide, pyridoxine hydrochloride, thiamine mononitrate and riboflavin in multivitamin with minerals tablets by reversed-phase ion-pair high performance liquid chromatography
Li K
Biomedical Chromatography, 16(8), 504-507 (2002)
Simultaneous determination of niacinamide, pyridoxine, riboflavin, and thiamine in multivitamin products by high-pressure liquid chromatography
Walker MC, et al.
Journal of Pharmaceutical Sciences, 70(1), 99-101 (1981)
Differential pulse polarographic method development and validation of riboflavin in pharmaceutical formulation
Kashid LM and Patil SV
International Journal of Scientific Research, 5(2), 325-334 (2015)
Riboflavin
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 5(2), 3484-3485 (2008)
Simultaneous determination of riboflavin phosphate and other ingredients in a multivitamin pharmaceutical preparation by on-line automated LC coupled with pre-column immobilized enzyme reactor
Ono M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(1-2), 325-334 (2002)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service