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USP

Riboflavin

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
(−)-Riboflavin, Lactoflavin, Vitamin B2, Vitamin G
Empirical Formula (Hill Notation):
C17H20N4O6
CAS Number:
83-88-5
Molecular Weight:
376.36
Beilstein:
97825
MDL number:
MFCD00005022
UNSPSC Code:
41116107
PubChem Substance ID:
329751041
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

riboflavin

manufacturer/tradename

USP

mp

290 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

InChI key

AUNGANRZJHBGPY-SCRDCRAPSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Riboflavin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, and standard stock Riboflavin solution for assay, identification, and performance test according to the given below monographs and general chapters of United States Pharmacopeia (USP):
  • Riboflavin
  • Riboflavin Tablets
  • Water-Soluble Vitamins Preparation
  • 〈481〉 Riboflavin Assay

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Phosphated Riboflavin, United States Pharmacopeia (USP) Reference Standard

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Riboflavin Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

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Riboflavin sodium phosphate, British Pharmacopoeia (BP) Reference Standard

PHR2570

Riboflavin Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Riboflavin Tablets
United States Pharmacopeia, 41(6), 3870-3870 (2017)
Water-Soluble Vitamins Preparation
United States Pharmacopeia, 45(5) (2021)
?481? Riboflavin Assay
United States Pharmacopeia, 41(6), 6735-6735 (2017)
Riboflavin
United States Pharmacopeia, 30(3), 3869-3869 (2013)
Nacim Bouheraoua et al.
Investigative ophthalmology & visual science, 55(11), 7601-7609 (2014-10-30)
We compared the efficacy and early morphological changes in the cornea following conventional (C-CXL), transepithelial by iontophoresis (I-CXL), and accelerated (A-CXL) collagen cross-linking in keratoconus. A total of 45 eyes of 45 patients with progressive keratoconus who underwent corneal collagen
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