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PHR2071

Supelco

Benzhydrol

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Diphenylmethanol, Diphenhydramine Impurity D, Benzhydrol, Benzhydryl alcohol, Diphenyl carbinol
Linear Formula:
(C6H5)2CHOH
CAS Number:
91-01-0
Molecular Weight:
184.23
Beilstein:
1424379
MDL number:
MFCD00004488
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. Y0000887
traceable to USP 1051602

API family

diphenhydramine, cyclizine

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

bp

297-298 °C (lit.)

mp

65-67 °C (lit.)

application(s)

pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

OC(c1ccccc1)c2ccccc2

InChI

1S/C13H12O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H

InChI key

QILSFLSDHQAZET-UHFFFAOYSA-N

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General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Benzhydrol is a commonly used precursor in the production of pharmaceutical drugs, such as antihistamines, antihypertensives, and antiallergens.

Application

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB8552 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Role of TiO2-based photocatalysts on the synthesis of the pharmaceutical precursor benzhydrol by UVA-LED radiation
Lopes JC, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 391, 112350-112350 (2020)

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