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PHR1115

Supelco

Stearyl Alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

1-Octadecanol, Octadecyl alcohol, Stearyl alcohol

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500 ML
CN¥1,193.48
2.5 L
CN¥4,463.74

CN¥1,193.48

Estimated to ship onApril 28, 2025Details

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500 ML
CN¥1,193.48
2.5 L
CN¥4,463.74

About This Item

Linear Formula:
CH3(CH2)17OH
CAS Number:
112-92-5
Molecular Weight:
270.49
Beilstein:
1362907
EC Number:
204-017-6
MDL number:
MFCD00002823
UNSPSC Code:
41116107
PubChem Substance ID:
329823136
NACRES:
NA.24

CN¥1,193.48

Estimated to ship onApril 28, 2025Details

Request a Bulk Order

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. S1350000
traceable to USP 1622000

vapor density

9.3 (vs air)

vapor pressure

<0.01 mmHg ( 38 °C)

API family

stearyl alcohol

CofA

current certificate can be downloaded

autoignition temp.

842 °F

expl. lim.

~8 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

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technique(s)

UV/Vis spectroscopy: suitable

technique(s)

GC-HS: suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

HPLC: suitable

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

liquid

form

liquid

form

liquid

form

liquid

UV absorption

λ: 270 nm Amax: ≤0.60, λ: 290 nm Amax: ≤0.10, λ: 330 nm Amax: ≤0.01, λ: 275 nm Amax: ≤0.22, λ: 300 nm Amax: ≤0.05

UV absorption

-

UV absorption

-

UV absorption

-

expl. lim.

15.2 %

expl. lim.

15.2 %

expl. lim.

15.2 %

expl. lim.

15.2 %

General description

Stearyl Alcohol is added as a stiffening agent in cosmetics and pharmaceutical formulations. It is also utilized to enhance the water-holding capacity of ointments. Its other applications include the use in controlled-release tablets, suppositories, and microspheres.[1]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Stearyl Alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography.[2]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7161 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

383.0 °F - closed cup

Flash Point(C)

195 °C - closed cup

  • Specification Sheet

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    Handbook of Pharmaceutical Excipients 6th edition Pharmaceutical Press (2009)
    Stearyl Alcohol
    USP43-NF38: United States Pharmacopeia and National Formulary
    United States Pharmacopeia/National Formulary, 40(2), 6072-6072 (2015)
    W B Rizzo et al.
    Biochemical medicine and metabolic biology, 50(1), 93-102 (1993-08-01)
    Patients with the autosomal recessive form of rhizomelic chondrodysplasia punctata (AR-RCDP) and other generalized peroxisomal disorders are deficient in the incorporation of fatty alcohol into plasmalogen lipids. To determine whether these patients accumulated fatty alcohol, we measured their plasma fatty
    Allergic contact dermatitis from stearyl alcohol in Efudix cream.
    P D Yesudian et al.
    Contact dermatitis, 45(5), 313-314 (2001-11-28)
    Jörg Bauer et al.
    Journal of the American Chemical Society, 127(20), 7296-7297 (2005-05-19)
    Hydrophobically assisted switching phase (HASP) synthesis is a concept that allows the choice between the advantages of solid-supported chemistry and those of solution-phase synthesis. Starting from the examination of adsorption and desorption properties of hydrophobic molecules to and from reversed-phase
    View All Related Papers

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