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PHR1133

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Cetyl Alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

1-Hexadecanol, Cetyl alcohol, Palmityl alcohol

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About This Item

Linear Formula:
CH3(CH2)15OH
CAS Number:
36653-82-4
Molecular Weight:
242.44
Beilstein:
1748475
EC Number:
253-149-0
MDL number:
MFCD00004760
UNSPSC Code:
41116107
PubChem Substance ID:
329823153
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. C0990000
traceable to USP 1103003

vapor density

8.34 (vs air)

vapor pressure

<0.01 mmHg ( 43 °C)

API family

cetyl alcohol

CofA

current certificate can be downloaded

autoignition temp.

483 °F

expl. lim.

8 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

179-181 °C/10 mmHg (lit.)

mp

48-50 °C (lit.)

density

0.818 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCCCCCCCCCCCCCCCO

InChI

1S/C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3

InChI key

BXWNKGSJHAJOGX-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Cetyl Alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7153 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Certificates of Analysis (COA)

Lot/Batch Number
LRAD4841
LRAD1857
LRAC8760
LRAB3383
P500133

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The application of chromatography to the analysis of pharmaceutical creams.
Van de Vaart FJ, et al.
Chromatographia, 16(1), 247-250 (1982)
HPLC-fluorescence determination of chlorocresol and chloroxylenol in pharmaceuticals.
Gatti R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 16(3), 405-412 (1997)
Dhanalakshmi S Anbukumar et al.
Journal of lipid research, 51(5), 1085-1092 (2009-12-19)
Neutrophils are important in the host response against invading pathogens. One chemical defense mechanism employed by neutrophils involves the production of myeloperoxidase (MPO)-derived HOCl. 2-Chlorohexadecanal (2-ClHDA) is a naturally occurring lipid product of HOCl targeting the vinyl ether bond of
Luca Lo Piccolo et al.
Applied and environmental microbiology, 77(4), 1204-1213 (2010-12-25)
Enzymes involved in oxidation of long-chain n-alkanes are still not well known, especially those in gram-positive bacteria. This work describes the alkane degradation system of the n-alkane degrader actinobacterium Gordonia sp. strain SoCg, which is able to grow on n-alkanes
Flávia C Carvalho et al.
Journal of pharmaceutical sciences, 99(5), 2367-2374 (2009-12-08)
The development of a controlled-release dosage form of zidovudine (AZT) is of crucial importance, in view of the pharmacokinetics of its toxic activity. A suitable drug delivery system could increase AZT bioavailability, reducing its dose-dependent side effects. In this study
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