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I1892

Supelco

Ibuprofen sodium salt

≥98% (GC)

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Synonym(s):
α-Methyl-4-(isobutyl)phenylacetic acid
Linear Formula:
C13H17O2Na
CAS Number:
31121-93-4
Molecular Weight:
228.26
EC Number:
250-477-6
MDL number:
MFCD00133414
UNSPSC Code:
41116107
PubChem Substance ID:
329815360
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98% (GC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

H2O: 100 mg/mL, clear to slightly hazy

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

[Na+].CC(C)Cc1ccc(cc1)C(C)C([O-])=O

InChI

1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1

InChI key

PTTPUWGBPLLBKW-UHFFFAOYSA-M

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

Related Categories

General description

Ibuprofen belongs to the class of non-steroidal anti-inflammatory drugs, widely used for the treatment of mild to moderate pain and several forms of arthritis.

Application

Ibuprofen sodium salt may be used as a model drug to study the intercalation mechanism via ion exchange reaction between ibuprofen and a biocompatible hydrotalcite compound.
Ibuprofen sodium salt may be used as an analytical reference standard for the qualification of the analyte in wastewaters using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Recommended products

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Emanuele Mauri et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 146, 143-149 (2019-11-15)
Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug (NSAID) commonly used in the treatment of pain, fever and inflammation. However, the administration of IBU in its free carboxylic acid form is strongly dependent on its limited solubility in aqueous solution. This
Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase dispersion?HPLC
Aguilar-Arteaga.K, et al.
Talanta, 80(3), 1152-1157 (2010)
Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents?I. Intercalation and in vitro release of ibuprofen
Ambrogi V, et al.
International Journal of Pharma Research & Review, 220, 23-32 (2001)
Mixed supramolecular hemimicelles aggregates and magnetic carrier technology for solid phase extraction of ibuprofen in environmental samples prior to its HPLC-UV determination
Beiraghi A, et al.
Chemical Engineering Science, 108(3), 103-110 (2014)
Abegaz Tizazu Andrgie et al.
Polymers, 12(11) (2020-11-12)
Hydrogels have been investigated as ideal biomaterials for wound treatment owing to their ability to form a highly moist environment which accelerates cell migration and tissue regeneration for prompt wound healing. They can also be used as a drug carrier
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