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Merck
CN

F6270

Fipexide hydrochloride

analytical standard

Synonym(s):

1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine

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About This Item

Empirical Formula (Hill Notation):
C20H21ClN2O4 · HCl
CAS Number:
Molecular Weight:
425.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
251-857-4
MDL number:
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InChI key

MVOWQBJZZKOQNU-UHFFFAOYSA-N

InChI

1S/C20H21ClN2O4.ClH/c21-16-2-4-17(5-3-16)25-13-20(24)23-9-7-22(8-10-23)12-15-1-6-18-19(11-15)27-14-26-18;/h1-6,11H,7-10,12-14H2;1H

SMILES string

Cl.Clc1ccc(OCC(=O)N2CCN(CC2)Cc3ccc4OCOc4c3)cc1

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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F Durand et al.
Journal of hepatology, 15(1-2), 144-146 (1992-05-01)
Fipexide belongs to a new class of cognition activators and is noted for its lack of amphetamin-like side effects. We describe three patients who developed fulminant hepatic failure less than 2 months after beginning fipexide administration. The mean interval from
[Fipexide: a new drug for the regulation of dopaminergic system at the macromolecular level].
C Missale et al.
Bollettino chimico farmaceutico, 122(2), 79-85 (1983-02-01)
M Genkova-Papasova et al.
Acta physiologica et pharmacologica Bulgarica, 14(4), 36-41 (1988-01-01)
Experiments on albino rats were carried out to study the effects of the nootropic drugs piracetam, aniracetam, meclofenoxate and fipexide on the DA-beta-hydroxylase inhibitor diethyldithiocarbamate- and the alpha 2-adrenoceptor agonist clonidine-impaired cognitive functions. The changes in memory were studied by
G Serra et al.
Pharmacological research, 21(5), 603-608 (1989-09-01)
The effect of fipexide, administered at different intervals after the learning trial of a single step-through type passive avoidance situation was studied. The administration of fipexide immediately after the learning trial resulted in a long-lasting facilitation of passive avoidance behaviour.
[Acute drug-induced hepatitis: a case of acute cytolysis after ingestion of fipexide].
F Mion et al.
Gastroenterologie clinique et biologique, 14(5), 513-514 (1990-01-01)

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