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BP617

Aspirin

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin

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About This Item

Linear Formula:
2-(CH3CO2)C6H4CO2H
CAS Number:
50-78-2
Molecular Weight:
180.16
EC Number:
200-064-1
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
779271
MDL number:
MFCD00002430

Key Documents

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Product Name

Aspirin, British Pharmacopoeia (BP) Reference Standard

InChI key

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

SMILES string

CC(=O)Oc1ccccc1C(O)=O

grade

pharmaceutical primary standard

API family

aspirin

form

crystalline

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

134-136 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Application

Aspirin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Aspirin Tablets
  • Aspirin Gastro-resistant Tablets
  • Co-codaprin Tablets
  • Aspirin Dispersible Tablets
  • Aspirin and Caffeine Tablets

    • Biochem/physiol Actions

    Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Exclamation mark
    GHS07

    signalword

    Warning

    Storage Class

    11 - Combustible Solids

    wgk

    WGK 1

    flash_point_f

    482.0 °F

    flash_point_c

    250 °C

    hcodes

    H302,H412

    Hazard Classifications

    Acute Tox. 4 Oral - Aquatic Chronic 3

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    RP-HPLC analysis of aspirin and clopidogrel bisulphate in combination.
    An K, et al.
    Indian Journal of Pharmaceutical Sciences, 69(4), 597-597 (2007)
    Validated ultra HPLC method for the simultaneous determination of atorvastatin, aspirin, and their degradation products in capsules.
    Vora D N, et al.
    Journal of Liquid Chromatography and Related Technologies, 31(18), 2821-2837 (2008)

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