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B5524

Supelco

Benzydamine hydrochloride

analytical standard

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Synonym(s):
1-Benzyl-3-(3-[dimethylamino]propoxy)-1H-indazole
Empirical Formula (Hill Notation):
C19H23N3O · HCl
CAS Number:
Molecular Weight:
345.87
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13

InChI

1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H

InChI key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

Gene Information

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

WGK

WGK 3


Certificates of Analysis (COA)

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Yildiz Yilmaz et al.
Xenobiotica; the fate of foreign compounds in biological systems, 49(5), 503-512 (2018-04-26)
The expression of flavin-containing monooxygenase (FMO) varies extensively between human and commonly used preclinical species such as rat and mouse. The aim of this study was to investigate the pulmonary FMO activity in rat using benzydamine. Furthermore, the contribution of
S Rossi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 74(2), 248-254 (2009-10-27)
The aim of the present work was the development of a thermally sensitive mucoadhesive gel based on chitosan derivatives for the treatment of oral mucositis. Trimethyl chitosan (TMC) and methylpyrrolidinone chitosan (MPC) were considered. They were mixed with glycerophosphate (GP)
F Capolongo et al.
Journal of veterinary pharmacology and therapeutics, 33(4), 341-346 (2010-07-22)
Benzydamine (BZ), a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, is metabolized in human, rat, cattle and rabbit to a wide range of metabolites. One of the main metabolites, BZ
Takeshi Sawada et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(5), 526-535 (2019-09-07)
1. Immunodeficient chimeric mice with humanised liver have been useful in predicting total clearance values of drugs in humans. However, their usefulness may currently be limited for specific compounds with interspecies differences.2. In vivo total clearance and in vitro hepatic
Koray Soygun et al.
The journal of advanced prosthodontics, 9(3), 200-207 (2017-07-07)
In this study, three bioceramic materials, [IPS Empress CAD (Ivoclar), IPS e.max CAD (Ivoclar), and Lava Ultimate CAD (3M ESPE)] were treated with three commercial mouthrinses [Listerine, Tantum Verde, and Klorhex]; and changes in colour reflectance and surface roughness values

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