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B2883

Sigma-Aldrich

bisBenzimide H 33258

≥98% (HPLC and TLC)

Synonym(s):

2′-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi(1H-benzimidazole) trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazole trihydrochloride, BBIH, BXI-72, HOE 33258, Hoechst 33258, NSC334072

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100 μG
¥6,364.93

¥6,364.93

Estimated to ship on2025年5月12日Details

A recombinant, preservative-free antibody is available for your target. Try ZRB1230
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100 μG
¥6,364.93

About This Item

Empirical Formula (Hill Notation):
C25H24N6O · 3HCl
CAS Number:
23491-45-4
Molecular Weight:
533.88
Beilstein:
4088183
EC Number:
245-690-6
MDL number:
MFCD00012679
UNSPSC Code:
12171500
PubChem Substance ID:
24891414
NACRES:
NA.47

¥6,364.93

Estimated to ship on2025年5月12日Details

A recombinant, preservative-free antibody is available for your target. Try ZRB1230
Request a Bulk Order

Quality Level

200

Assay

≥98% (HPLC and TLC)

form

powder

mp

280 °C

solubility

H2O: 10 mg/mL
water and ethanol: 10 mg/mL
phosphate buffer: precipitates

suitability

passes application test for fluorescence

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(=NCc3c2)c4ccc5NC(=NCc5c4)c6ccc(O)cc6

InChI

1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18;;;;/h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31);3*1H;1H2

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antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

serum

Gene Information

human ... ITGB1(3688)

Gene Information

human ... ITGB1(3688)

Gene Information

human ... ITGB1(3688)

Gene Information

human ... ITGB1(3688)

species reactivity

human

species reactivity

human

species reactivity

rhesus macaque, horse, human, pig, canine, bovine, sheep

species reactivity

mouse, rat, pig, human

biological source

mouse

biological source

mouse

biological source

rat

biological source

rabbit

UniProt accession no.

P05556

UniProt accession no.

P05556

UniProt accession no.

P05556

UniProt accession no.

P05556

Application

bisBenzimide H 33258 has been used for nuclear staining in cells.[1][2][3]
bisBenzimide H 33258 is useful for staining DNA, chromosomes and nuclei. bisBenzimide H 33258 may be used for fluorescence microscopy or flow cytometry.
Excitation max. = 346 nm
Emission max. = 460 nm
bisBenzimide H 33258 is useful for staining DNA, chromosomes, and nuclei. May be used for fluorescence microscopy or flow cytometry.

Biochem/physiol Actions

bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor.
bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor. bisBenzimide H 33258 is a membrane-permeable, fluorescent DNA stain with low cytotoxicity that intercalate in A-T regions of DNA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    0000401273
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    0000401275
    0000344833

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    Scientific reports, 9(1), 10924-10924 (2019-07-31)
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