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Merck
CN

P4170

Sigma-Aldrich

碘化丙啶

≥94.0% (HPLC)

别名:

3,8-二氨基-5-[3-(二乙基甲基氨基)丙基]-6-苯基菲啶二碘化物

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About This Item

经验公式(希尔记法):
C27H34I2N4
CAS号:
分子量:
668.39
Beilstein:
3843838
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥94.0% (HPLC)

表单

powder

mp

220-225 °C (dec.) (lit.)

储存温度

2-8°C

SMILES字符串

[I-].[I-].CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14

InChI

1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1

InChI key

XJMOSONTPMZWPB-UHFFFAOYSA-M

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一般描述

碘化丙啶(PI)是一种荧光染料,可用于核酸染色。无法通过活细胞或完整细胞。可轻易进入死细胞、濒死细胞或膜受损细胞。碘化丙啶可轻松结合DNA。

应用

碘化丙啶用于:流式细胞术检测细胞周期,γH2AX和pH3分析,肝星状细胞(HSC)的凋亡试验,加入染色缓冲液/溶液中染色细胞以分析细胞周期

特点和优势

该化合物是细胞凋亡研究的特色产品。点击此处以了解更多的细胞凋亡特色产品。可访问sigma.com/discover-bsm了解更多关于用于其他研究领域生物活性小分子。

象形图

Health hazard

警示用语:

Warning

危险声明

危险分类

Muta. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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分析证书(COA)

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访问文档库

Robin Kumar et al.
Methods in molecular biology (Clifton, N.J.), 2279, 213-223 (2021-03-09)
Annexin V and propidium iodide staining is widely used for determining the cellular death through apoptosis. In the presence of Ca2+ ions, annexin V has a strong binding affinity for phosphatidylserine, a membrane phospholipid that during apoptosis is translocated from
Haiying Liu et al.
Frontiers in cell and developmental biology, 9, 684857-684857 (2021-10-05)
It has been reported that calpain/caspase-mediated apoptosis induced by endoplasmic reticulum stress (ERS) in hepatic stellate cells (HSCs) by previous studies. At present, the activation of HSC is an important cause of liver fibrosis, and the induction of HSC apoptosis
Aswathy Shailaja et al.
Biofilm, 4, 100090-100090 (2022-11-18)
Filamentous fungi are ubiquitous and frequent components of biofilms. A means to visualize them and quantify their viability is essential for understanding their development and disruption. However, quantifying filamentous fungal biofilms poses challenges because, unlike yeasts and bacteria, they are
Julia Burrill et al.
Forensic science international. Genetics, 46, 102269-102269 (2020-03-11)
Forensic DNA typing from touched or handled items in routine casework is increasing as the sensitivity of detection techniques improves. Our understanding of the cellular/acellular content of touch deposits and the origins of the DNA therein is still limited. This
Wei Liang et al.
Molecular immunology, 112, 312-321 (2019-06-24)
Precise glycosylation plays a crucial and distinctive role in thymic T cell development. The core fucosylation is dramatically up-regulated at the transition from CD4-CD8- (DN) to CD4+CD8+ (DP) in the thymic development. Ablation of core fucosylation in T cells did

商品

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

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