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Merck
CN

A1202000

Citric acid

anhydrous, European Pharmacopoeia (EP) Reference Standard

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About This Item

Linear Formula:
HOC(COOH)(CH2COOH)2
CAS Number:
Molecular Weight:
192.12
Beilstein:
782061
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

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grade

pharmaceutical primary standard

Agency

EP reference standard

API family

citric acid

quality

anhydrous

expl. lim.

8 %, 65 °F

manufacturer/tradename

EDQM

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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1 of 4

This Item
88597H100918304
grade

for inorganic trace analysis, for ultratrace analysis

grade

-

grade

-

grade

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

form

liquid

form

solution

form

liquid

form

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

anion traces

bromide (Br-): ≤10 μg/kg, fluoride (F-): ≤1000 μg/kg, phosphate (PO43-): ≤25 μg/kg, chloride (Cl-): ≤25 μg/kg, sulfate (SO42-): ≤50 μg/kg, nitrate (NO3-): ≤250 μg/kg

anion traces

-

anion traces

-

anion traces

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Citric acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Certificates of Analysis (COA)

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Wei-An Lai et al.
Journal of molecular endocrinology, 53(2), 259-270 (2014-07-25)
Estrogens are essential for female reproduction and overall well-being, and estrogens in the circulation are largely synthesized in ovarian granulosa cells. Using primary cultures of ovarian granulosa cells from gonadotropin-primed immature rats, we have recently discovered that pituitary FSH and
Yohei Nakayama et al.
Journal of oral science, 56(4), 261-268 (2014-12-17)
Amelotin (AMTN) is a secreted protein transcribed predominantly during the maturation stage of enamel formation and localized in the junctional epithelium. We investigated differences in the levels of AMTN gene expression between non-inflamed gingiva and inflamed gingiva from patients with
Konrad Hoetzenecker et al.
European heart journal, 36(11), 676-685 (2013-01-17)
Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients.
Tetsuji Sawada et al.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 18(1), 119-128 (2014-02-04)
The G-Project committee was erected by the Japan Society for Gastroenterological Carcinogenesis with an aim of establishing a new classification scheme based on molecular biological characteristics that would supplement the conventional TNM classification to better predict outcome. In a literature
Levente Karaffa et al.
Applied microbiology and biotechnology, 61(3), 189-196 (2003-04-17)
This Mini-Review summarizes the current knowledge on the biochemical and physiological events leading to massive citric acid accumulation by Aspergillus niger under industrially comparable conditions, thereby particularly emphasizing the roles of glycolytic flux and its control, excretion of citric acid

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