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Agency
BP
JP
Ph. Eur.
USP
质量水平
管理合规性
FCC
蒸汽压
<0.1 hPa ( 20 °C)
产品线
EMPROVE® ESSENTIAL
方案
99.5-100.5% substance (anhydrous) basis (alkalimetric)
表单
fine powder
效能
3000 mg/kg LD50, oral (Rat)
expl. lim.
8 %, 65 °F
pH值（酸碱度）
1.7 (20 °C, 100 g/L in H2O)
pKa
(1) 3.13, (2) 4.76, (3) 6.4
沸点
200 °C/1013 hPa (decomposition)
mp
153-159 °C (lit.)
溶解性
1330 g/L
密度
1.665 g/cm3 at 18 °C
痕量阳离子
Al: ≤0.2 ppm
As: ≤1 ppm
Hg: ≤1 ppm
Pb: ≤0.5 ppm
heavy metals (as Pb): ≤5 ppm
应用
liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation
储存温度
2-30°C
SMILES字符串
OC(=O)CC(O)(CC(O)=O)C(O)=O
InChI
1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI key
KRKNYBCHXYNGOX-UHFFFAOYSA-N
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一般描述
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
应用
Citric acid is typically used as pH adjuster, buffer agent or as antioxidant in pharmaceutical formulations. Its application range spans across different formulation types, including semi-solid dosage forms, liquid dosage forms such as solutions and solid dosage forms such as effervescent tablets or granules.
Citric acid anhydrous powder Emprove® Essential is citric acid present in its water-free, powder form.
Citric acid anhydrous powder Emprove® Essential is citric acid present in its water-free, powder form.
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
通常也和此产品一起购买
产品编号
说明
价格
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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