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902292

Sigma-Aldrich

EvanPhos

greener alternative

≥95%

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Synonym(s):
Biaryl phosphine ligand for Pd catalysis, Dicyclohexyl(2,6-dimethoxy-3-(2-methoxynaphthalen-1-yl)phenyl)phosphane
Empirical Formula (Hill Notation):
C31H39O3P
CAS Number:
2223634-83-9
Molecular Weight:
490.61
UNSPSC Code:
12161600
NACRES:
NA.22

Assay

≥95%

form

powder or crystals

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

131-133 °C

functional group

phosphine

greener alternative category

Aligned,

Related Categories

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

EvanPhos is a new biaryl phosphine ligand designed in the Lipshutz Lab as a Pd-complexed pre-catalyst for Suzuki-Miyaura cross couplings. Micellar catalysis was demonstrated with the surfactant TPGS-750-M, 2 wt. % in H2O (cat# 733857) and is an attractive technology for greener chemistry.

Other Notes

EvanPhos: a ligand for ppm level Pd-catalyzed Suzuki–Miyaura couplings in either organic solvent or water

Watch Professor Lipshutz talk about greener chemistry in this webinar: From milligrams to kilograms: synthetic chemistry following nature′s lead

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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