51197
Sodium formate solution
suitable for LC-MS, LiChropur™
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Linear Formula:
HCOONa
CAS Number:
Molecular Weight:
68.01
Beilstein:
3723428
MDL number:
UNSPSC Code:
41116105
NACRES:
NB.21
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quality
LiChropur™
concentration
10 mM NaOH in isopropanol/water 1:1 (+0.2% HCOOH)
technique(s)
LC/MS: suitable
suitability
suitable for LC-MS
SMILES string
[Na+].[O-]C=O
InChI
1S/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1
InChI key
HLBBKKJFGFRGMU-UHFFFAOYSA-M
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General description
Sodium formate solution is commonly used as a mobile phase additive in liquid chromatography-mass spectrometry (LC-MS).
Features:
Features:
- Extensive QC testing ensures the highest specifications.
- Optimized to improve ionization and resolution.
- Extremely low levels of inorganic and organic impurities.
- Manufactured specifically for accurate and fast LC-MS.
Application
Sodium formate may be used as a mobile phase additive in the following:
- enantiomeric separation of acidic compounds by nano-liquid chromatography (Nano-LC) technique
- determination of ambrisentan enantiomers in commercial samples of active pharmaceutical ingredients (API) using high-performance liquid chromatography (HPLC) technique
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
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Certificates of Analysis (COA)
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Rapid determination of ambrisentan enantiomers by enantioselective liquid chromatography using cellulose?based chiral stationary phase in reverse phase mode
Dousa M and Gibala P
Journal of Separation Science, 35(7), 798-803 (2012)
Anna Rocco et al.
Journal of separation science, 32(10), 1696-1703 (2009-04-17)
Some racemic nonsteroidal anti-inflammatory drugs, namely naproxen, indoprofen, ketoprofen, flurbiprofen, carprofen, cicloprofen, flunoxaprofen and suprofen were separated into their enantiomers by nano-LC. Chiral recognition was achieved adding to the mobile phase heptakis (2,3,6-tri-O-methyl)-beta-cyclodextrin (TM-beta-CD). Capillary columns of 100 microm id
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