Key Documents
Safety Information
80457
Trifluoroacetic acid
eluent additive for LC-MS, LiChropur™, ≥99.0% (GC)
Synonym(s):
TFA
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About This Item
Recommended Products
vapor density
3.9 (vs air)
Quality Level
vapor pressure
97.5 mmHg ( 20 °C)
Assay
≥99.0% (GC)
form
liquid
technique(s)
LC/MS: suitable
impurities
≤0.05% water
≤50 mg/kg total sulfur (as SO4)
refractive index
n20/D 1.3 (lit.)
bp
72.4 °C (lit.)
mp
−15.4 °C (lit.)
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Related Categories
1 of 4
This Item | 91707 | T6508 | 618729 |
|---|---|---|---|
| assay ≥99.0% (GC) | assay ≥99.0% (GC) | assay 99% | assay - |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form liquid | form liquid | form liquid | form - |
| refractive index n20/D 1.3 (lit.) | refractive index n20/D 1.3 (lit.) | refractive index n20/D 1.3 (lit.) | refractive index - |
| density 1.489 g/mL at 20 °C (lit.) | density 1.489 g/mL at 20 °C (lit.) | density 1.489 g/mL at 20 °C (lit.) | density - |
General description
Features:
- Extensive QC testing ensures the highest specifications.
- Optimized to improve ionization and resolution.
- Extremely low levels of inorganic and organic impurities.
- Manufactured specifically for accurate and fast LC-MS.
Application
Packaging
Legal Information
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Storage Class Code
8B - Non-combustible corrosive hazardous materials
WGK
WGK 2
Flash Point(F)
>212.0 °F - Pensky-Martens closed cup
Flash Point(C)
> 100 °C - Pensky-Martens closed cup
Regulatory Information
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Articles
The article describes the use of difluoroacetic acid (DFA) as an effective alternative to acid modifiers, formic acid (FA) and trifluoroacetic acid (TFA) in the LC-UV/MS analysis of proteins.
Compare columns in resolving medium-sized antibody fragments after digestion with DTT or IdeS using Reversed-Phase Chromatography for analysis.
Discover the efficient separation six nitrosamine impurities with high reproducibility and precise detection to ensure accurate analysis for regulatory compliance.
Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.
Protocols
Straightforward HPTLC-MS analysis of lactose in dairy products (milk or yoghurt) using only protein crash, centrifugation and dilution as sample preparation.
SEC-MS protocol for rapid glycoprofiling of monoclonal antibodies with antibody purification and mass spectrometer calibration.
A complete workflow for the intact and middle-up mass analysis of reduced and non-reduced monoclonal antibodies based on SEC-MS with sample preparation by protein-A affinity clean-up.
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