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Key Documents

Safety Information

484407

Sigma-Aldrich

1-Methoxy-2-propanol

greener alternative

≥99.5%

Synonym(s):

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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2 L
¥3,207.82
4 X 4 L
¥16,804.89

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Available to ship on2025年4月14日Details


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2 L
¥3,207.82
4 X 4 L
¥16,804.89

About This Item

Linear Formula:
CH3CH(OH)CH2OCH3
CAS Number:
Molecular Weight:
90.12
Beilstein:
1731270
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

application(s):
microbiology
bp:
118-119 °C (lit.)
vapor pressure:
10.9 mmHg ( 25 °C)

¥3,207.82


Available to ship on2025年4月14日Details


Request a Bulk Order

vapor density

3.12 (vs air)

Quality Level

vapor pressure

10.9 mmHg ( 25 °C)

product line

ReagentPlus®

Assay

≥99.5%

form

liquid

autoignition temp.

532 °F

expl. lim.

13.8 %

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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1 of 4

This Item
48443165692901255
Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

application(s)

microbiology

application(s)

-

application(s)

environmental

application(s)

-

solubility

water: miscible

solubility

water: soluble 198 g/L at 20 °C

solubility

-

solubility

-

form

liquid

form

-

form

-

form

liquid

bp

118-119 °C (lit.)

bp

145-146 °C (lit.)

bp

118-119 °C (lit.)

bp

-

General description

1-Methoxy-2-propanol (Propylene glycol methyl ether, PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.[1] Its degradation by microorganisms in different soil types has been investigated.[2] An oral reference dose (RfD) and an inhalation reference concentration (RfC) values of PGME have been obtained from inhalation studies in F344 rats and B6C3F1 mice.[3]
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry.Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

88.7 °F - closed cup - (External MSDS)

Flash Point(C)

31.5 °C - closed cup - (External MSDS)

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

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Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
R A Corley et al.
Toxicology letters, 156(1), 193-213 (2005-02-12)
Propylene glycol monomethyl ether (PM), along with its acetate, is the most widely used of the propylene glycol ether family of solvents. The most common toxic effects of PM observed in animal studies include sedation, very slight alpha(2u)-globulin mediated nephropathy
Nancy B Hopf et al.
Toxicology letters, 211(1), 77-84 (2012-03-17)
Aging adults represent the fastest growing population segment in many countries. Physiological and metabolic changes in the aging process may alter how aging adults biologically respond to pollutants. In a controlled human toxicokinetic study (exposure chamber; 12 m³), aging volunteers
J Y Domoradzki et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 31-39 (2003-07-15)
The kinetic equivalency of propylene glycol monomethyl ether (PGME), derived from propylene glycol monomethyl ether acetate (PGMEA), as well as the parent compound (PGME) following intravenous administration to Fischer 344 rats was evaluated. In addition, in vitro hydrolysis rates of

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