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Merck
CN

06676

Methoxypolyethylene glycol amine

2,000, extent of labeling: ≥0.4 mmol/g NH2 loading

Synonym(s):

O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine

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About This Item

Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
80506-64-5
UNSPSC Code:
12162002
PubChem Substance ID:
24845957
NACRES:
NA.22
MDL number:
MFCD00131599

Key Documents

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Product Name

Methoxypolyethylene glycol amine, 2,000, extent of labeling: ≥0.4 mmol/g NH2 loading

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

form

powder

extent of labeling

≥0.4 mmol/g NH2 loading

Quality Level

100

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Application

Methoxypolyethylene glycol amine (mPEG-NH2) can be used:
  • As a supporting material in the synthesis of polymer-lipid conjugates.
  • As an initiator for ring-opening polymerization (ROP) of N-substituted N-carboxy anhydrides (NNCAs) to prepare polypeptoids.

Other Notes

Soluble polymer support for peptide synthesis; Preparation of various conjugates containing polyethylene glycol; Review

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN8630
BCCN6955
BCCN1149
BCCL8097
BCCL5502

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Synthesis of Poly (ethylene glycol)-Polydiacetylene Conjugates and Their Micellar and Chromic Characteristics
Choi H et al.
Journal of Nanoscience and Nanotechnology, 8(10), 5104-5108 (2008)
Schiff base and reductive amination reactions of α-amino acids: a facile route toward N-alkylated amino acids and peptoid synthesis
Fu X, et al.
Polym. Chem., 9(37), 4617-4624 (2018)
M. Mutter et al.
Reactive Polymers, 6, 99-99 (1987)
R Colombo et al.
Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 362(10), 1385-1391 (1981-10-01)
The liquid-phase synthesis of two pentapeptides corresponding to the amino acid sequence of Leu- and Met-enkephalin is described. Modified monofunctional poly(ethylene glycol) containing a p-alkoxybenzyl alcohol functional group was employed as the soluble polymeric support. Cleavage of the peptides from
M. Leonard et al.
Tetrahedron, 40, 1581-1581 (1984)
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