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03762

Sigma-Aldrich

2,6-Di-tert-butyl-4-methylphenol

tested according to Ph. Eur.

Synonym(s):

Butylhydroxytoluenum, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC

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500 G
CN¥1,461.35

CN¥1,461.35

Available to ship onApril 23, 2025Details

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500 G
CN¥1,461.35

About This Item

Linear Formula:
[(CH3)3C]2C6H2(CH3)OH
CAS Number:
128-37-0
Molecular Weight:
220.35
Beilstein:
1911640
EC Number:
204-881-4
MDL number:
MFCD00011644
UNSPSC Code:
12352300
PubChem Substance ID:
329747800
NACRES:
NA.21

CN¥1,461.35

Available to ship onApril 23, 2025Details

Request a Bulk Order

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

200

vapor density

7.6 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

autoignition temp.

878 °F

bp

265 °C (lit.)

mp

69-73 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

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1 of 4

This Item
7591834750B1378
2,6-Di-tert-butyl-4-methylphenol tested according to Ph. Eur.

03762

2,6-Di-tert-butyl-4-methylphenol

2,6-Di-tert-butyl-4-methylphenol certified reference material, TraceCERT&#174;, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

75918

2,6-Di-tert-butyl-4-methylphenol

2,6-Di-tert-butyl-4-methylphenol purum, &#8805;99.0% (GC)

34750

2,6-Di-tert-butyl-4-methylphenol

2,6-Di-tert-butyl-4-methylphenol &#8805;99.0% (GC), powder

B1378

2,6-Di-tert-butyl-4-methylphenol

mp

69-73 °C (lit.)

mp

69-73 °C (lit.)

mp

68-72 °C, 69-73 °C (lit.)

mp

69-73 °C (lit.)

bp

265 °C (lit.)

bp

265 °C (lit.)

bp

265 °C (lit.)

bp

265 °C (lit.)

agency

USP/NF

agency

-

agency

-

agency

-

vapor density

7.6 (vs air)

vapor density

7.6 (vs air)

vapor density

7.6 (vs air)

vapor density

7.6 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

vapor pressure

<0.01 mmHg ( 20 °C)

vapor pressure

<0.01 mmHg ( 20 °C)

vapor pressure

<0.01 mmHg ( 20 °C)

Application


  • Quantitative analysis of residual butylated hydroxytoluene and butylated hydroxyanisole in Salmo salar, milk, and butter by liquid chromatography-tandem mass spectrometry.: This study provides a quantitative analysis of residual 2,6-Di-tert-butyl-4-methylphenol (BHT) and butylated hydroxyanisole (BHA) in various food products. The research highlights the presence and concentration of these antioxidants in fish, milk, and butter, demonstrating their widespread use in food preservation (Galal et al., 2024).

  • The key factors of solid nanodispersion for promoting the bioactivity of abamectin.: This research investigates the use of BHT in solid nanodispersions to enhance the bioactivity of abamectin, a widely used insecticide. The study identifies key factors that improve the stability and effectiveness of the formulation, suggesting applications in agricultural biotechnology (Ding et al., 2024).

Pictograms

Environment
GHS09

Signal Word

Warning

Hazard Statements

H410

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

260.6 °F - open cup

Flash Point(C)

127 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCM0249
    BCCL8467
    BCCK0141
    BCCJ7793
    BCCH6932

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    Li Li et al.
    Circulation, 105(7), 861-867 (2002-02-21)
    Current epidemiological data suggest that dental infections affecting tooth-supporting tissues (periodontitis) can disseminate into the systemic circulation and thereby contribute to atherosclerosis progression. To test this hypothesis, we investigated the effect of repeated systemic inoculations with Porphyromonas gingivalis (Pg), a
    I Björkhem et al.
    Arteriosclerosis and thrombosis : a journal of vascular biology, 11(1), 15-22 (1991-01-01)
    Rabbits fed a 1% cholesterol diet with or without the antioxidant butylated hydroxytoluene (BHT) developed typical atherosclerotic lesions. The addition of BHT gave higher levels of total cholesterol (+40%), triglycerides (+250%), low density lipoprotein (LDL), and very low density lipoprotein
    A M Vijesh et al.
    European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)
    In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized
    Gen-ichiro Arimura et al.
    Plant physiology, 146(3), 965-973 (2008-01-01)
    Continuous mechanical damage initiates the rhythmic emission of volatiles in lima bean (Phaseolus lunatus) leaves; the emission resembles that induced by herbivore damage. The effect of diurnal versus nocturnal damage on the initiation of plant defense responses was investigated using
    Butylated hydroxytoluene (BHT): a review.
    H Babich
    Environmental research, 29(1), 1-29 (1982-10-01)
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