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Key Documents

8.22021

Sigma-Aldrich

2,6-Di-tert-butyl-4-methylphenol

for synthesis

Synonym(s):

2,6-Di-tert-butyl-4-methylphenol

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About This Item

Empirical Formula (Hill Notation):
C15H24O
CAS Number:
Molecular Weight:
220.35
MDL number:
UNSPSC Code:
12352104
EC Index Number:
204-881-4
NACRES:
NA.22

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vapor pressure

0.02 hPa ( 20 °C)

Quality Level

Assay

≥99.0% (GC)

form

crystals

autoignition temp.

345 °C

potency

>2000 mg/kg LD50, oral (Rat)

bp

265 °C/1013 hPa

mp

69-70 °C

transition temp

flash point 127 °C

density

1.05 g/cm3 at 20 °C

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This Item
AP307FAP120FAQ503F
species reactivity

human

species reactivity

rabbit

species reactivity

human

species reactivity

human

biological source

goat

biological source

goat

biological source

goat

biological source

goat

antibody form

affinity purified immunoglobulin

antibody form

affinity purified immunoglobulin

antibody form

F(ab′)2 fragment of affinity isolated antibody

antibody form

purified antibody

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

Application

  • In silico, in vitro, in vivo Evaluation of Antioxidant Activity and Toxic Effects of Phosphorus-Containing Derivatives of 2, 6-Di-tert-Butylphenol: This study explores the antioxidant activities and potential toxicity of novel phosphorus-containing derivatives of 2,6-di-tert-butyl-4-methylphenol, providing valuable insights for drug discovery applications (MA Polovinkina et al., 2019).
  • Voltammetric Determination of Nitro Derivative of Synthetic Antioxidant 2,6-di-tert-butyl-4-methyl-phenol: This paper presents a method for determining the nitro derivative of 2,6-di-tert-butyl-4-methylphenol, highlighting its relevance in quality control in manufacturing processes (J Chýlková et al., 2016).
  • Facile synthesis of 2, 6-di-tert-butylphenol modified polystyrene and its antioxidative properties as the heterogeneous antioxidant: Discusses the synthesis of a modified polystyrene incorporating 2,6-di-tert-butyl-4-methylphenol to enhance its antioxidative properties, which is critical for applications in material science (Y Fu et al., 2023).
  • A theoretical determination of the composition of by-products obtained in the production of butylated hydroxytoluene from 2, 6-di-tert-butylphenol: This research offers a theoretical analysis of by-products formed during the synthesis of butylated hydroxytoluene, which is important for optimizing industrial chemical processes (RR Syrlybaeva et al., 2015).
  • Anti-inflammatory activity of the artificial antioxidants 2-tert-butyl-4-methoxyphenol (BHA), 2, 6-di-tert-butyl-4-methylphenol (BHT) and 2, 4, 6-tri-tert-butylphenol (TBP): Evaluates the anti-inflammatory effects of 2,6-di-tert-butyl-4-methylphenol and related compounds, which could inform their therapeutic uses (Y Murakami et al., 2015).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 69 °C
Melting range (upper value): ≤ 72 °C
Identity (IR): passes test

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

260.6 °F - open cup

Flash Point(C)

127 °C - open cup


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