Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

00583

Sigma-Aldrich

Nitrous oxide

≥99.998%

Sign Into View Organizational & Contract Pricing

Synonym(s):
Dinitrogen monoxide, Laughing gas
Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
Beilstein:
8137358
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22

vapor density

1.53 (15 °C, vs air)

vapor pressure

51.7 mmHg ( 21 °C)

Assay

≥99.998%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Nitrous oxide can be used as:
  • A nitrogen donor to synthesize alkynyl and alkenyl substituted triazenes by coupling reaction with lithium amides and organomagnesium compounds.
  • A reagent to synthesize azoimidazolium dyes.

N2O can also be reacted with N-heterocyclic olefins (NHOs) to form electron-rich azo-bridged NHO dimers.

Packaging

pressure tin
filling pressure at 15°C: 11 bar; content (15°C, 1 bar): 11 l

Other Notes

Sales restrictions may apply

Signal Word

Danger

Hazard Statements

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of azoimidazolium dyes with nitrous oxide
Tskhovrebov AG, et al.
Angewandte Chemie (International Edition in English), 127, 1305-1308 (2015)
Synthesis of triazenes with nitrous oxide
Kiefer G, et al.
Angewandte Chemie (International Edition in English), 54, 302-305 (2015)
Synthesis of organic super-electron-donors by reaction of nitrous oxide with n-heterocyclic olefins
Eymann LYM, et al.
Journal of the American Chemical Society, 141, 17112-17116 (2019)
Klaus Butterbach-Bahl et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1621), 20130122-20130122 (2013-05-29)
Although it is well established that soils are the dominating source for atmospheric nitrous oxide (N2O), we are still struggling to fully understand the complexity of the underlying microbial production and consumption processes and the links to biotic (e.g. inter-
G Imberger et al.
British journal of anaesthesia, 112(3), 410-426 (2014-01-11)
The role of nitrous oxide in modern anaesthetic practice is contentious. One concern is that exposure to nitrous oxide may increase the risk of cardiovascular complications. ENIGMA II is a large randomized clinical trial currently underway which is investigating nitrous

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service