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Safety Information

30-5000

Sigma-Aldrich

Tris Base

≥99.0%, solid, JIS special grade

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Synonym(s):
Tris Base, Tris(hydroxymethyl)aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
Linear Formula:
NH2C(CH2OH)3
CAS Number:
77-86-1
Molecular Weight:
121.14
Beilstein:
741883
MDL number:
MFCD00004679
UNSPSC Code:
12352116
PubChem Substance ID:
329753524

product name

Tris(hydroxymethyl)aminomethane, JIS special grade, ≥99.0%

grade

JIS special grade

Assay

≥99.0%

form

solid

availability

available only in Japan

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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Application


  • Composition of the Sheath of Sphaerotilus Natans.: This study analyzes the sheath structure of Sphaerotilus natans, potentially utilizing Tris(hydroxymethyl)aminomethane in the process, to explore its biochemical and microbiological aspects (Romano et al., 1963).

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Corey A Baron et al.
Magnetic resonance in medicine, 73(3), 1075-1084 (2014-04-12)
An acquisition method that does not increase scan time or specific absorption rate is investigated for reducing the deleterious effects of cerebrospinal fluid (CSF) partial volume effects on diffusion tensor imaging (DTI) tractography. It is based on using a shorter
Filippo Bertoli et al.
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Nanoparticles in contact with cells and living organisms generate quite novel interactions at the interface between the nanoparticle surface and the surrounding biological environment. However, a detailed time resolved molecular level description of the evolving interactions as nanoparticles are internalized
D R Brocks et al.
Clinical pharmacokinetics, 23(6), 415-427 (1992-12-01)
Ketorolac is a new chiral nonsteroidal anti-inflammatory drug (NSAID) which is marketed for analgesia as the racemate. The drug is administered as the water soluble tromethamine salt and is available in tablets or as an intramuscular injection. The absorption of
Sylvain Clède et al.
Chemical communications (Cambridge, England), 48(62), 7729-7731 (2012-06-29)
A rhenium tris-carbonyl derivative has been designed to couple infrared and luminescent detection in cells. Both spectroscopies are consistent with one another; they point out the reliability of the present SCoMPI (for Single Core Multimodal Probe for Imaging) for bimodal
Wei Li et al.
Biosensors & bioelectronics, 70, 304-309 (2015-04-04)
DNA methylation catalyzed by methyltransferase (MTase) plays an important role in many biological processes, including gene transcription, genomic imprinting and cellular differentiation. Herein, a simple and novel homogeneous electrochemical strategy for ultrasensitive DNA MTase activity assay has been successfully developed
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