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Key Documents

10108294001

Roche

Phosphoenol-pyruvate

97% (PEP-K), pkg of 1 g

Synonym(s):

Phospho(enol)pyruvic acid monopotassium salt, 2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K

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1 G
¥3,065.51

¥3,065.51


Available to ship on2025年4月27日Details



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1 G
¥3,065.51

About This Item

Empirical Formula (Hill Notation):
C3H4KO6P
CAS Number:
Molecular Weight:
206.13
Beilstein:
4603446
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:

¥3,065.51


Available to ship on2025年4月27日Details


description

C3H4O6PK (Formula)
PEP, monopotassium salt

Quality Level

Assay

97% (PEP-K)

form

solid

mol wt

Mr 168.0 (PEP)
Mr 206.1 (PEP-K)

packaging

pkg of 1 g

manufacturer/tradename

Roche

storage temp.

2-8°C

SMILES string

[K+].OC(=O)C(=C)OP(O)([O-])=O

InChI

1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1

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1 of 4

This Item
P3637P7127P0564
assay

97% (PEP-K)

assay

≥97% (enzymatic)

assay

≥97% (enzymatic)

assay

≥97% (enzymatic)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

solid

form

powder

form

powder

form

powder

description

C3H4O6PK (Formula)

description

-

description

-

description

-

mol wt

Mr 168.0 (PEP)

mol wt

-

mol wt

-

mol wt

-

General description

Contents: 80% PEP (enzymatic)

Application

Phosphoenolpyruvate (PEP) has been used in:
  • glutamate-cysteine ligase activity[1]
  • v-ATPase enzyme activity assay[2]
  • meso kinase assay[3]

Substrate for pyruvate kinase.

Biochem/physiol Actions

Phosphoenolpyruvate (PEP) plays a vital role in metabolism.[4] It has a high phosphate group-transfer potential and it serves a versatile C3-synthon in C–C, C–P and C–O bond-formation reactions. PEP acts as a substrate for pyruvate kinase (PK) in the last step of glycolysis.[4]

Other Notes

For life science research only. Not for use in diagnostic procedures.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes.
    Garcia A, et al.
    FEBS Journal, 269(13), 3226-3236 (2002)
    Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells.
    Desideri E
    Autophagy, 8(12), 1769-1781 (2012)
    Maria B Bagh et al.
    Nature communications, 8, 14612-14612 (2017-03-08)
    Defective lysosomal acidification contributes to virtually all lysosomal storage disorders (LSDs) and to common neurodegenerative diseases like Alzheimer's and Parkinson's. Despite its fundamental importance, the mechanism(s) underlying this defect remains unclear. The v-ATPase, a multisubunit protein complex composed of cytosolic
    Jasmine M Hershewe et al.
    Nature communications, 12(1), 2363-2363 (2021-04-24)
    Cell-free gene expression (CFE) systems from crude cellular extracts have attracted much attention for biomanufacturing and synthetic biology. However, activating membrane-dependent functionality of cell-derived vesicles in bacterial CFE systems has been limited. Here, we address this limitation by characterizing native
    Brian S Muntean et al.
    Cell reports, 34(5), 108718-108718 (2021-02-04)
    The G protein alpha subunit o (Gαo) is one of the most abundant proteins in the nervous system, and pathogenic mutations in its gene (GNAO1) cause movement disorder. However, the function of Gαo is ill defined mechanistically. Here, we show

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