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MAB5574

Sigma-Aldrich

Anti-NMDAR2B Antibody

ascites fluid, clone 1B3.3B6, Chemicon®

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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

1B3.3B6, monoclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

Specificity

NMDAR2B, C-terminal. By Western blot the antibody reacts with bands at ~170 and ~90 kDa on rat brain lysate.

Immunogen

Recombinant protein from rat NMDAR2B.

Application

Detect NMDAR2B using this Anti-NMDAR2B Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:1,000-1:5,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Physical form

Liquid

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Rat forebrain or cerebellum.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Ilaria Bertocchi et al.
Communications biology, 4(1), 59-59 (2021-01-10)
The NMDA receptor-mediated Ca2+ signaling during simultaneous pre- and postsynaptic activity is critically involved in synaptic plasticity and thus has a key role in the nervous system. In GRIN2-variant patients alterations of this coincidence detection provoked complex clinical phenotypes, ranging from

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