Skip to Content

Dear Customer:

The current international situation is complex and volatile, and the tariff policy remains unclear, which may have a certain impact on the prices of our products. Under these circumstances, we hope to have a friendly communication with you regarding the order matters.

Given the current uncertainties, if you choose to place an order during this period, we reserve the right to adjust the price based on the actual situation. At the same time, we understand that the market changes may bring you some inconvenience. Therefore, if there is a significant price fluctuation due to changes in the tariff policy before the actual delivery of the order, Merck will negotiate with you and adjust or cancel the order as the situation requires.

Merck
CN
All Photos(1)

Key Documents

MAB388

Sigma-Aldrich

Anti-Myelin Proteolipid Protein Antibody, CT, clone PLPC1

clone PLPC1, Chemicon®, from mouse

Synonym(s):

PLP

Sign Into View Organizational & Contract Pricing

Select a Size

100 μG
CN¥6,895.36

CN¥6,895.36

Estimated to ship onApril 29, 2025Details

Sign In for Best Price
Request a Bulk Order
All Photos(1)

Select a Size

Change View
100 μG
CN¥6,895.36

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CN¥6,895.36

Estimated to ship onApril 29, 2025Details

Sign In for Best Price
Request a Bulk Order

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

PLPC1, monoclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

NM_000533.3

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
AB15454WH0005354M5MAB4163
Anti-Myelin Proteolipid Protein Antibody, CT, clone PLPC1 clone PLPC1, Chemicon®, from mouse

MAB388

Anti-Myelin Proteolipid Protein Antibody, CT, clone PLPC1

Anti-Proteolipid Protein Antibody Chemicon®, from chicken

AB15454

Anti-Proteolipid Protein Antibody

Monoclonal Anti-PLP1 antibody produced in mouse clone 4H8, purified immunoglobulin, buffered aqueous solution

WH0005354M5

Monoclonal Anti-PLP1 antibody produced in mouse

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MC57 clone MC57, Chemicon®, from mouse

MAB4163

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MC57

biological source

mouse

biological source

chicken

biological source

mouse

biological source

mouse

Gene Information

human ... PLP1(5354)

Gene Information

human ... PLP1(5354)

Gene Information

human ... PLP1(5354)

Gene Information

human ... ABCB1(5243)

antibody form

purified immunoglobulin

antibody form

affinity purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable

technique(s)

ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

flow cytometry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice

Specificity

Reacts with myelin proteolipid protein in many mammalian species. Shows cross-reactivity to DM20.

Immunogen

Epitope: C-terminus
Myelin proteolipid protein, synthetic peptide CGRGTKF corresponding to the C-terminal peptide.

Application

Detect Myelin Proteolipid Protein using this Anti-Myelin Proteolipid Protein Antibody, C-terminus, clone PLPC1 validated for use in IH, IH(P) & WB.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins
Western Blotting: detects a 23-25kDa protein and DM20 a 20kDa protein; PLP can aggregate causing HMW bands to sometimes appear in certain preparations.

Immunocytochemistry: 4% PFA fixed cells, 5-10 minutes room temperature. Use 0.1% triton in block only to allow antibody access to C-terminal epitope.

Immunohistology on fresh frozen sections or 4% PFA fixed, frozen tissues. Epitope is internal, use 0.1-0.2% triton X-100 in the blocking step for permeabilization.

Immunohistochemistry in paraffin: works best with lightly fixed tissues, or Bouin′s fixed material, although there are reports of traditional formalin fixation also working with antigen recovery. {Mathis, et al 2003}.

Optimal working dilutions must be determined by end user.

Target description

23-25 kDa

Linkage

Replaces: MAB388

Physical form

Format: Purified
Protein A purified
Purified mouse immunoglobulin in PBS, pH 7.2 containing 0.09% sodium azide.

Storage and Stability

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Brain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

    • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Sachiko Homma et al.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(30), 7974-7986 (2007-07-27)
    The heat shock transcription factors (Hsfs) are responsible for the heat shock response, an evolutionarily conserved process for clearance of damaged and aggregated proteins. In organisms such as Caenorhabditis elegans, which contain a single Hsf, reduction in the level of
    Raquel Bello-Morales et al.
    PloS one, 6(5), e19388-e19388 (2011-05-17)
    The velocity of the nerve impulse conduction of vertebrates relies on the myelin sheath, an electrically insulating layer that surrounds axons in both the central and peripheral nervous systems, enabling saltatory conduction of the action potential. Oligodendrocytes are the myelin-producing
    Tapas Makar et al.
    Stem cell research & therapy, 9(1), 127-127 (2018-05-04)
    Adult bone marrow contains stem cells that replenish the myeloid and lymphoid lineages. A subset of human and mouse CD34+ bone marrow stem cells can be propagated in culture to autonomously express embryonic stem cell genes and embryonic germ layer
    Tuancheng Feng et al.
    Brain : a journal of neurology, 143(7), 2255-2271 (2020-06-24)
    TMEM106B encodes a lysosomal membrane protein and was initially identified as a risk factor for frontotemporal lobar degeneration. Recently, a dominant D252N mutation in TMEM106B was shown to cause hypomyelinating leukodystrophy. However, how TMEM106B regulates myelination is still unclear. Here
    Aline M Thomas et al.
    NeuroImage, 204, 116245-116245 (2019-10-13)
    Multiple sclerosis (MS) is an autoimmune disorder that targets myelin proteins and results in extensive damage in the central nervous system in the form of focal lesions as well as diffuse molecular changes. Lesions are currently detected using T1-weighted, T2-weighted
    View All Related Papers

    Articles

    Derivation of Functional Oligodendrocyte Progenitor Cells (OPCs) from Human Neural Stem Cell Lines

    Derivation and characterization of functional human neural stem cell derived oligodendrocyte progenitor cells (OPCs) that efficiently myelinate primary neurons in culture.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service