ABT241
Anti-acetyl Tubulin (Lys40) Antibody
from rabbit, purified by affinity chromatography
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Synonym(s):
Tubulin alpha-1A chain, Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-3 chain
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
rat (based on 100% sequence homology), bovine (based on 100% sequence homology), mouse (based on 100% sequence homology)
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys40)
Gene Information
human ... TUBA1A(7846)
General description
Tubulin is the major constituent of microtubules, and microtubules are major cytoskeletal elements. Tubulin proteins undergo a number of post-translational modifications both during individual synthesis and after complete tubule formation. Acetylation of alpha chains at Lys-40 stabilizes microtubules and affects the affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling.
Immunogen
Epitope: Near N-Terminus
KLH-conjugated linear peptide corresponding to a region near the near N-Terminus of human Tubulin acetylated at Lys40.
Application
Anti-acetyl Tubulin (Lys40) Antibody is an antibody against acetyl Tubulin (Lys40) for use in western blotting.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Quality
Evaluated by Western Blotting in untreated and Trichostatin A treated HeLa cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected acetyl Tubulin (Lys40) in 10 µg of Trichostatin A treated HeLa cell lysate, and not in untreated HeLa cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected acetyl Tubulin (Lys40) in 10 µg of Trichostatin A treated HeLa cell lysate, and not in untreated HeLa cell lysate.
Target description
~50 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Joseph M Varberg et al.
mSphere, 1(1) (2016-06-16)
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