Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, rat
species reactivity (predicted by homology)
human (sequence homology 14/15)
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TXN(7295)
Specificity
Recognizes Thioredoxin 1 (TRX1).
Immunogen
Synthetic peptide from rat/mouse Thioredoxin 1.
Application
Detect Thioredoxin 1 using this Anti-Thioredoxin 1 Antibody validated for use in WB.
Immunoblotting: 1:1,000-1:5,000 using ECL. Reacts with the ~12-14 kD thioredoxin 1 protein. Additional bands >30 kD may been seen.
Suggested dilution and blocking buffer is TBST containing 5% non-fat milk. Suggested gel percentage is 15%. Suggested incubation time is overnight.
Suggested dilution and blocking buffer is TBST containing 5% non-fat milk. Suggested gel percentage is 15%. Suggested incubation time is overnight.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Oxidative Stress
Oxidative Stress
Linkage
Replaces: MABN1090
Physical form
Rabbit serum. Liquid. Contains no preservative.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Xiaoqin Zhao et al.
Acta biochimica et biophysica Sinica, 46(4), 318-329 (2014-03-01)
Cardiac complications are the leading cause of death in diabetes. However, the mechanism of diabetes in inducing myocardial injury and apoptosis, and whether the thioredoxin (Trx) system is involved remain unclear. In this study, male Sprague-Dawley rats were randomly divided
Chiara Milanese et al.
Nature communications, 10(1), 4887-4887 (2019-10-28)
Accumulation of DNA lesions causing transcription stress is associated with natural and accelerated aging and culminates with profound metabolic alterations. Our understanding of the mechanisms governing metabolic redesign upon genomic instability, however, is highly rudimentary. Using Ercc1-defective mice and Xpg
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