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8.52099

Sigma-Aldrich

Fmoc-Lys(Dnp)-OH

Novabiochem®

Synonym(s):

Fmoc-Lys(Dnp)-OH, N-α-Fmoc-N-ε-2,4-dinitrophenyl-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C27H26N4O8
CAS Number:
Molecular Weight:
534.52
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥97.0% (HPLC)
≥98% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

InChI

1S/C27H26N4O8/c32-26(33)24(11-5-6-14-28-23-13-12-17(30(35)36)15-25(23)31(37)38)29-27(34)39-16-22-20-9-3-1-7-18(20)19-8-2-4-10-21(19)22/h1-4,7-10,12-13,15,22,24,28H,5-6,11,14,16H2,(H,29,34)(H,32,33)/t24-/m0/s1

InChI key

OENCMORJQAUAAJ-DEOSSOPVSA-N

General description

A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc SPPS.The Dnp group is the preferred quencher for use in conjunction with the Mca fluorophore, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Chromogenic Labeling of Synthetic Peptides

Linkage

Replaces: 04-12-1239

Analysis Note

Color (visual): slight yellow to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -13.5 - -10.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

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Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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