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907383

Sigma-Aldrich

Fmoc-L-Photo-Lysine

≥95%

Synonym(s):

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine

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1 MG
CN¥3,997.53

CN¥3,997.53

Available to ship onApril 27, 2025Details

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1 MG
CN¥3,997.53

About This Item

Empirical Formula (Hill Notation):
C26H30N4O6
CAS Number:
2250437-42-2
Molecular Weight:
494.54
UNSPSC Code:
12352209

CN¥3,997.53

Available to ship onApril 27, 2025Details

Request a Bulk Order

Assay

≥95%

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

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storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

recombinant

expressed in CHO cells

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Application

Fmoc-L-Photo-Lysine is a diazirine-containing, Fmoc-protected lysine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907251.

Other Notes

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

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Description
Pricing

96885

Z-Lys(Z)-OSu, ≥95.0% (HPLC)

55788

Nα-Fmoc-Nε-Dabcyl-L-lysine, technical, ≥90% (HPLC)

73749

Nα-Fmoc-Nε-biotinyl-L-lysine, ≥95.0% (HPLC)

F4061

Fmoc-Lys(Mca)-OH

900751

Biotinylated-D-lysine TFA salt

907294

Fmoc-L-Photo-Phe-OH, ≥95%

907324

Fmoc-L-photo-proline, ≥95%

907251

H-L-Photo-lysine HCl, ≥98%

907278

H-L-Photo-leucine HCl, ≥98%

907286

H-L-Photo-Proline hydrochloride, ≥95%

907340

H-L-Photo-Phe-OH, ≥98%

907367

Fmoc-L-photo-methionine, ≥95%

907375

H-L-Photo-methionine HCl, ≥95%

907391

Fmoc-L-photo-leucine, ≥98%

8.52097

Fmoc-Lys(biotin)-OH, Novabiochem®

8.52096

Fmoc-Lys(Dabcyl)-OH, Novabiochem®

8.52326

Fmoc-azidolysine, Novabiochem®

8.52095

Fmoc-Lys(Mca)-OH, Novabiochem®

8.52100

Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH, Novabiochem®

8.52099

Fmoc-Lys(Dnp)-OH, Novabiochem®

914339

Fmoc-L-Lys(Nvoc)-OH, ≥98%

914088

N6-((2-Azidoethoxy)carbonyl)-L-lysine hydrochloride, ≥95%

914827

N6-((Prop-2-yn-1-yloxy)carbonyl)-L-lysine hydrochloride, ≥98%

915793

Methyl-o-nitropiperonyllysine, ≥95%

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    MKCK5469

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