1.52025
Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns
L × I.D. 5 mm x 4.6 mm Guard Cartridges (3 pieces)
Synonym(s):
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces)
About This Item
product name
Chromolith® HighResolution RP-18 endcapped, L × I.D. 5 mm x 4.6 mm guard cartridges (3 pieces)
material
PEEK column
Quality Level
Agency
suitable for ISO/CEN 6304.09
suitable for USP L1
product line
Chromolith®
feature
endcapped
endcapped
packaging
pkg of 3 ea
extent of labeling
15% Carbon loading
18% Carbon loading
parameter
200 bar pressure
400 bar pressure
45 °C max. temp.
50 °C max. temp.
technique(s)
HPLC: suitable
HPLC: suitable
LC/MS: suitable
mass spectrometry (MS): suitable (High)
mass spectrometry (MS): suitable (High)
column L × I.D.
0.5 cm × 4.6 mm
surface area
250 m2/g × 250 m2/g
matrix
highly porous
monolithic silica
monolithic silica
matrix active group
C18 bonding phase, octadecylsilane (ODS)
C18 bonding phase
pore size
1.15 μm macroporosity
1.5 μm macroporosity
15 nm mesoporosity
15 nm mesoporosity
operating pH range
2-7.5
2-7.5
separation technique
reversed phase
storage temp.
no temp limit
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General description
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges are extremely easy to use. The guard cartridges are simply added directly in front of the main column to protect it from chemical or mechanical contamination. Due to the benefits of monolithic technology, and the convenience of Chromolith® guard columns, they are also popular for use with classical particulate columns. Moreover, guard columns can be used as trap columns when large sample volumes are to be injected. Guard columns should be changed frequently in order to avoid excessive accumulation of impurities.
Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges are used with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]
Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns
All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument
Application
- A Novel and Sensitive LC-MS/MS Method for the Quantitation of Ceftiofur in Pharmaceutical Preparations and Milk Samples.: This study, conducted by Levent S, Özcan S, Geven A, and Can NÖ, presents a new LC-MS/MS method utilizing Chromolith® HighResolution RP-18 endcapped columns. The method provides high sensitivity and specificity for the quantitation of ceftiofur, a veterinary antibiotic, in both pharmaceutical preparations and milk samples, demonstrating its potential for robust analytical applications in pharmaceutical and food safety contexts (Levent et al., 2021).
Legal Information
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Articles
Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.
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