14-377-M
MKK4/SKK1 Protein, active, 10 µg
Active, N-terminal GST tagged, murine MKK4 residues 34-end, for use in Kinase Assays.
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UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
biological source
mouse
Quality Level
100
300
mol wt
Mw 67.7 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Gene Information
mouse ... MAP2K4(26398)
General description
N-terminal GST tagged, murine MKK4 residues 34-end
Product Source: expressed in E. coli
Biochem/physiol Actions
Protein Target: MKK4
Target Sub-Family: STE
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-377M when ordering the 250 µg size.
Quality
routinely evaluated by phosphorylation of ATF2 substrate
Physical form
Purified using glutathione agarose. Activated by incubation with MEKK and then re-purified using Ni2+/NTA agarose
Storage and Stability
6 months at -70C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif
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