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1.37002

SAFC

Citric acid

anhydrous powder, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Pharma Manufacturing

Synonym(s):

2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

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5 NMOL
CN¥821.80

CN¥821.80

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5 NMOL
CN¥821.80

About This Item

Linear Formula:
HOC(COOH)(CH2COOH)2
CAS Number:
77-92-9
Molecular Weight:
192.12
Beilstein:
782061
MDL number:
MFCD00011669
UNSPSC Code:
12352106
EC Index Number:
201-069-1

CN¥821.80

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Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

500

vapor pressure

<0.1 hPa ( 20 °C)

product line

EMPROVE® EXPERT

Assay

99.5-100.5% substance (anhydrous) basis (alkalimetric)

form

fine powder
solid

feature

RNase and DNase free

expl. lim.

8 %, 65 °F

technique(s)

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

pH

1.7 (20 °C, 100 g/L in H2O)

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C6745C8374C5533
Human Collagen Type IV

CC076

Human Collagen Type IV

Collagen Type IV from human cell culture Bornstein and Traub Type IV, 0.3&#160;mg/mL, sterile-filtered, BioReagent, suitable for cell culture

C6745

Collagen Type IV from human cell culture

Collagen from human placenta Bornstein and Traub Type IV, powder

C8374

Collagen from human placenta

Collagen from human placenta Bornstein and Traub Type IV, powder, BioReagent, suitable for cell culture

C5533

Collagen from human placenta

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | stem cell: suitable

technique(s)

cell culture | mammalian: suitable

concentration

1 mg/mL

concentration

0.3 mg/mL

concentration

-

concentration

-

assay

95% (Human collagen type IV, SDS-PAGE)

assay

-

assay

>85% (SDS-PAGE)

assay

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

form

liquid

form

solution

form

powder

form

powder

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Citric acid anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Citric acid anhydrous Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

    • What is the Emprove® Program?

    The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

    Material Qualification Dossier

    Free of charge - Sign in to download

    Quality Management Dossier (Open Access)

    Free of charge - Sign in to download

    Operational Excellence Dossier

    Available by subscription or for a fee

    Operational Excellence Dossier

    Available by subscription or for a fee

    Learn more about the benefits an Emprove® Program subscription can provide
    Why are these documents unavailable?
    Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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