Skip to Content
Merck
CN

03-0160-00

SMC® Human IL-1β High Sensitivity Immunoassay Kit

Used for ultrasensitive quantification of Human IL-1β in human serum and plasma

Synonym(s):

IL-1 beta Single Molecule Counting Kit, IL-1 beta immunoassay kit, IL-1 beta ultra-sensitive immunoassay, Interleukin-1 beta immunoassay kit

Sign In to View Organizational & Contract Pricing

Select a Size


About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

product line

SMC®

usage

 kit sufficient for 96 wells

species reactivity

human

manufacturer/tradename

SMC®

technique(s)

single molecule counting: suitable

input

plasma (K2 EDTA)
serum

UniProt accession no.

compatibility

for use with FemtoQuest and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

General description

Interleukin-1 beta (IL-1β) is a pro-inflammatory cytokine produced mainly by activated macrophages and other immune cells. It plays a pivotal role in mediating inflammatory responses, promoting the activation of immune cells, and influencing the production of other cytokines. IL-1β is also involved in various physiological processes, including fever induction and the regulation of immune system responses, making it a key player in both health and disease.

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Biochem/physiol Actions

Although IL-1β was detectable in non-human primate, rat, equine, feline and canine samples, the assay has not been verified for these species.

Features and Benefits

  • High-Performance Sensitivity: The SMC®technology excels in the quantification of IL-1β in human serum and plasma, enabling highly accurate measurements.
  • Built for Confidence: With low variability and high reproducibility, you can trust your data across experiments. Whether you′re profiling inflammation or validating biomarkers, this assay delivers consistent, high-quality results.
  • Deeper Insights into Inflammation: IL-1β is a key player in autoimmune diseases, neuroinflammation, and sepsis. This assay helps you explore its role with unmatched clarity.
  • Early Biomarker Detection: The ultra-sensitive performance supports early-stage discovery and therapeutic development.

Packaging

96 well assay

Analysis Note

  • Sensitivity: LLOQ 200 fg/mL* (SMCxPRO® Instrument
  • Standard Curve Range: 50-50,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Serum: 107% Plasma: 111%
  • Recovery: Serum: 85% Plasma: 83%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & Immunology Inflammatory Disease Immune Response Autoimmune Disease

Legal Information

FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

新产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

通过适合的免疫检测产品,探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。

Reduce sources of error and variability in sensitive methods to quantify biomarkers by automating the SMC® immunoassay workflow with the Hamilton Microlab® STARlet liquid handling workstation.

Learn how immunoassays are used in cosmetics and personal care research to discover potential harmful effects of cosmetics products, and assess markers of inflammation, sensitization, aging, and tissue regeneration among others.

Use the power of high sensitivity immunology assays with SMC® technology to precisely characterize low-abundant cytokines like those from Th1/Th2 and Th17 cells.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service