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Merck
CN

03-0156-00

SMC® Human IL-13 High Sensitivity Immunoassay Kit

Used for ultrasensitive quantification of Human IL-13 in human serum and plasma

Synonym(s):

IL-13 Single Molecule Counting Kit, IL-13 ultra-sensitive immunoassay, Interleukin-13 immunoassay kit, NC30 immunoassay kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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Product Name

SMC® Human IL-13 High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Human IL-13 in human serum and plasma

technique(s)

single molecule counting: suitable

product line

SMC®

usage

 in. sufficient for 96 wells

species reactivity

human

manufacturer/tradename

SMC®

input

serum
plasma (K2 EDTA)

UniProt accession no.

compatibility

for use with FemtoQuest and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

Analysis Note

  • Sensitivity: LLOQ 40 fg/mL* (SMCxPRO® Instrument
  • Standard Curve Range: 20-100,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Serum: 95% Plasma: 100%
  • Recovery: Serum: 88% Plasma: 89%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & Immunology Inflammatory Disease Immune Response Autoimmune Disease

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Biochem/physiol Actions

Although IL-13 was detectable in guinea pig, non-human primate, rat, rabbit and canine samples, the assay has not been verified for these species.

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

  • Unparalleled Sensitivity: The SMC®technology delivers exceptional performance in quantifying IL-13 in human serum and plasma, enabling precise measurements.
  • Enhanced Research Insights: The ability to detect low levels of IL-13 provides valuable insights into immune responses, inflammation, and disease mechanisms.
  • Cost-Effective: By allowing for the detection of low-abundance cytokines, these assays can reduce the need for larger sample volumes and repeated testing, ultimately saving time and resources.
  • Streamlined Laboratory Operations: The kit′s design and features enhance workflow efficiency, allowing researchers to focus on data generation rather than preparation.

General description

Interleukin 13 (IL-13) is secreted by a number of cells including T helper cells, CD4 cells and a various white blood cells and is thought to be a mediator of allergic inflammation in many tissues via the induction of IgE synthesis by B cells. Although primarily associated with the induction of airway disease, IL-13 has also been shown to inhibit the production of proinflammatory cytokines by monocytes and macrophages suggesting it has important anti-inflammatory properties.

Packaging

96 well assay

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

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Certificates of Analysis (COA)

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Related Content

Use the power of high sensitivity immunology assays with SMC® technology to precisely characterize low-abundant cytokines like those from Th1/Th2 and Th17 cells.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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