Skip to Content
Merck
CN
All Photos(1)

Documents

880120P

Avanti

18:0 PEG2000 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
474922-77-5
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 g (880120P-1g)
pkg of 1 × 200 mg (880120P-200mg)
pkg of 1 × 25 mg (880120P-25mg)
pkg of 1 × 500 mg (880120P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

General description

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000 (18:0 PEG2000 PE) is conjugate, covalently attached to polyethylene glycol (PEG2000). It forms a stable micelle of 180kDa with phosphoethanolamine as hydrophobic core and hydrophilic PEG2000 as outer micelle surface.

Application

18:0 PEG2000 PE may be used in the nickel resin functionalization of quantum dots. It may also be used in liposome preparation.

Biochem/physiol Actions

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000 (18:0 PEG2000 PE) is an effective drug carrier and is biocompatible. PEG stabilizes and protects the micelle from phagocytic system. The use of PEG as a conjugate with phospholipids enables improved liposome preparation and effective drug encapsulation.

Packaging

20 mL Clear Glass Screw Cap Vial (880120P-1g)
20 mL Clear Glass Screw Cap Vial (880120P-500mg)
5 mL Amber Glass Screw Cap Vial (880120P-200mg)
5 mL Amber Glass Screw Cap Vial (880120P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

C8667

Cholesterol, Sigma Grade, ≥99%

10901393001

Glycogen, from mussels

11636090910

PCR DIG Probe Synthesis Kit, sufficient for 25 reaction (50 μL final reaction volume)

11603558001

DIG Easy Hyb™, suitable for hybridization, solution

HIL2-RO

Interleukin-2, human (hIL-2), recombinant (E. coli)

700000P

Cholesterol (ovine), Avanti Research™ - A Croda Brand

700001P

DC-Cholesterol HCl, Avanti Research™ - A Croda Brand 700001P, powder

810150P

18:1 Liss Rhod PE, Avanti Research™ - A Croda Brand

840455P

16:0 PG, Avanti Research™ - A Croda Brand

840875P

18:1 PA, Avanti Research™ - A Croda Brand

850150P

18:1 PI(3)P, Avanti Research™ - A Croda Brand

850345P

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

850355P

16:0 PC (DPPC), Avanti Research™ - A Croda Brand

850365P

18:0 PC (DSPC), Avanti Research™ - A Croda Brand

850375C

18:1 (Δ9-Cis) PC (DOPC), Avanti Research™ - A Croda Brand

850375P

18:1 (Δ9-Cis) PC (DOPC), Avanti Research™ - A Croda Brand

850457C

16:0-18:1 PC, Avanti Research™ - A Croda Brand

850457P

16:0-18:1 PC, Avanti Research™ - A Croda Brand

850465P

18:0-16:0 PC, 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine, powder

850725P

18:1 (Δ9-Cis) PE (DOPE), Avanti Research™ - A Croda Brand

880135P

DSPE-PEG(2000) Carboxylic Acid, Avanti Research™ - A Croda Brand 880135P, powder

890890P

18:1 TAP (DOTAP), Avanti Research™ - A Croda Brand

840051P

Egg PC, Avanti Research™ - A Croda Brand

860065P

Ganglioside GM1 (Ovine Brain), Avanti Research™ - A Croda Brand

880126P

DSPE-PEG(2000) Maleimide, Avanti Research™ - A Croda Brand 880126P, powder

880128P

DSPE-PEG(2000) Amine, Avanti Research™ - A Croda Brand

880129P

DSPE-PEG(2000) Biotin, Avanti Research™ - A Croda Brand 880129P, powder

880150P

14:0 PEG2000 PE, Avanti Research™ - A Croda Brand 880150P, powder

880220P

18:0 PEG5000 PE, Avanti Research™ - A Croda Brand 880220P, powder

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes
Graham SM, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 178, 101-107 (2014)
Structure and dynamics of highly PEG-ylated sterically stabilized micelles in aqueous media
Vukovic L, et al.
Journal of the American Chemical Society, 133(34), 13481-13488 (2011)
P A Melnikov et al.
Bulletin of experimental biology and medicine (2019-11-24)
We studied the effect of IL-1β on the permeability of brain capillaries in healthy mice. Intravital microscopy demonstrated that parenteral administration of IL-1β was followed by an increase in vascular permeability ensuring passage of free Alexa488 fluorescent label through the
Ling Ye et al.
Nanotheranostics, 3(1), 54-65 (2019-01-22)
Rationale: Despite growing use of engineered nanomaterials (ENM) in applications from electronics to medicine, the potential risk to human health remains a critical concern within clinical use. ENM exposure during pregnancy can potentially cause reproductive toxicity even at levels that
Kathleen Cullion et al.
Pharmaceutical research, 36(12), 179-179 (2019-11-11)
It is unknown whether there are sex differences in response to free or encapsulated local anesthetics. We examined nerve block duration and toxicity following peripheral nerve blockade in male and female rats. We studied the local anesthetic bupivacaine (free or
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service