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880150P

Avanti

14:0 PEG2000 PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

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About This Item

CAS Number:
474922-82-2
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

14:0 PEG2000 PE, Avanti Research™ - A Croda Brand 880150P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (880150P-1g), pkg of 1 × 200 mg (880150P-200mg), pkg of 1 × 25 mg (880150P-25mg), pkg of 1 × 500 mg (880150P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880150P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C125H248NO55P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-123(127)178-120-122(181-124(128)27-25-23-21-19-17-15-13-11-9-7-5-2)121-180-182(130,131)179-29-28-126-125(129)177-119-118-176-117-116-175-115-114-174-113-112-173-111-110-172-109-108-171-107-106-170-1

InChI key

QQHAAYKTQQJGGW-YMNXLSEASA-N

General description

14:0 PEG2000 PE, also called as 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DMPE-PEG2000), is a polyethylene glycol (PEG)-phospholipid conjugate. It belongs to a group of polymerizable lipids. Incorporation of DMPE-PEG in the vesicle formulation stops aggregation of vesicles upon peptide addition.

Application

14:0 PEG2000 PE or 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in: giant vesicles preparation, lipid nanoparticle (LNP) formulation, unilamellar liposomes preparation for small-angle X-ray scattering (SAXS) experiments

Packaging

20 mL Clear Glass Screw Cap Vial (880150P-1g)
20 mL Clear Glass Screw Cap Vial (880150P-500mg)
5 mL Amber Glass Screw Cap Vial (880150P-200mg)
5 mL Amber Glass Screw Cap Vial (880150P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Josefine Eilsø Nielsen et al.
Biochimica et biophysica acta. Biomembranes, 1861(7), 1355-1364 (2019-04-13)
The naturally occurring peptide indolicidin from bovine neutrophils exhibits strong biological activity against a broad spectrum of microorganisms. This is believed to arise from selective interactions with the negatively charged cytoplasmic lipid membrane found in bacteria. We have investigated the
Pedro P G Guimaraes et al.
Journal of controlled release : official journal of the Controlled Release Society, 316, 404-417 (2019-11-05)
Messenger RNA (mRNA) has recently emerged as a promising class of nucleic acid therapy, with the potential to induce protein production to treat and prevent a range of diseases. However, the widespread use of mRNA as a therapeutic requires safe
L Limozin et al.
The European physical journal. E, Soft matter, 10(4), 319-330 (2004-03-12)
We studied the formation of actin scaffolds in giant vesicles of dimyristoylphosphatidylcholine (DMPC). Polymerization of actin was induced at low ionic strength through ionophore-mediated influx of Mg2+ (2 mM). The spatial organization of the filamentous actin was visualized by confocal
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Global Trade Item Number

SKUGTIN
880150P-25MG04061835187768
880150P-1G04061835187744
880150P-200MG04061835187751
880150P-500MG04061835187775